- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price on Sep 14
$117
Average ticket price on Sep 14
$144
Fastest journey on Sep 14
17 h 15 m
Average journey duration on Sep 14
18 h 54 m
Buses on Sep 14
12
Distance
725 km
The best way to find a cheap bus ticket from Ancona to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Ancona to Prague will cost around $144 if you buy it on the day, but the cheapest tickets can be found for only $117.
It's difficult to get from Ancona to Prague without transferring at least once.
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FlixBus · FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from Ancona to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $165 For those with little time, consider booking a flight, which has an average total journey time of 4h 55m. Average ticket prices depend on the travel mode: a bus costs an average of $165, while a flight costs an average of $577.
Distance: 450 miles (725 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$165 Average price Cheapest | $577 Average price | $236 Average price | $297 Average price (fuel + tolls) |
18h 18m Average total duration 17h 48m Onboard + 30m Additional time* | 4h 55m Average total duration Fastest 2h 55m Onboard + 2h 0m Additional time* | 17h 39m Average total duration 17h 9m Onboard + 30m Additional time* | 12h 6m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Ancona to Prague:
A bus is $71 (€58) less than a train for this route with tickets for a train from Ancona to Prague costing on average $236 (€191).
A bus is $412 (€334) less than a flight for this route with tickets for a flight from Ancona to Prague costing on average $577 (€467).
Other travel options to Prague take longer:
Train takes on average 17h 9m.
Bus takes on average 17h 48m.
Tickets start at around $165 (€133) compared to roughly $297 (€240) in fuel and tolls — a saving of about $132 (€107). The journey takes 17h 48m versus 12h 6m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:30AM | Arrival Time 03:15AM | Duration 22h45 | Departure days Mon, Fri | Cheapest price $107 |
Operator FlixBus | Departure Time 04:50AM | Arrival Time 05:45AM | Duration 24h55 | Departure days Mon, Sun | Cheapest price $117 |
Operator FlixBus | Departure Time 05:30AM | Arrival Time 05:45AM | Duration 24h15 | Departure days Fri, Sat | Cheapest price $99 |
Operator FlixBus | Departure Time 07:20AM | Arrival Time 07:10AM | Duration 23h50 | Departure days Everyday | Cheapest price $80 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 09:25AM | Duration 18h40 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $86 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 04:10PM | Duration 21h15 | Departure days Everyday | Cheapest price $81 |
The table below shows live departures for Ancona to Prague buses for today, Sunday, September 13. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 6:55 PM Ancona, Via Guglielmo Marconi / SS681 | 21h15 | 4:10 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus | 6:55 PM Ancona, Via Guglielmo Marconi / SS681 | 17h15 | 12:10 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 6:55 PM Ancona, Via Guglielmo Marconi / SS681 | 17h30 | 12:25 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 6:55 PM Ancona, Via Guglielmo Marconi / SS681 | 22h40 | 5:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 6:55 PM Ancona, Via Guglielmo Marconi / SS681 | 21h50 | 4:45 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:30 AM Ancona, Via Guglielmo Marconi / SS681 | 22h45 | 3:15 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 4:50 AM Ancona, Via Guglielmo Marconi / SS681 | 24h55 | 5:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 7:20 AM Ancona, Via Guglielmo Marconi / SS681 | 23h50 | 7:10 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 7:20 AM Ancona, Via Guglielmo Marconi / SS681 | 23h40 | 7:00 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 2:45 PM Ancona, Via Guglielmo Marconi / SS681 | 22h45 | 1:30 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus | 2:45 PM Ancona, Via Guglielmo Marconi / SS681 | 18h40 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 2:45 PM Ancona, Via Guglielmo Marconi / SS681 | 19h50 | 10:35 AM Prague, Central Train Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Ancona to Prague run on average 16 times per day, taking around 17h 48m. Cheap bus tickets for this journey start at $71 (€57) if you book in advance.
The earliest bus runs at 01:00, the last at 23:50. The fastest bus covers the 450 miles (725 km) distance in 15h 55m.
Distance 450 miles (725 km) |
Average bus duration 17h 48m |
Cheapest ticket price $71 (€57) |
Buses per day 16 |
Fastest bus 15h 55m |
First bus 1:00 AM |
Last bus 11:50 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Apr - Jun |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 1 day |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Ancona to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Ancona to Prague buses use the Ancona, Via Guglielmo Marconi / SS681 to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Hlavní Nádraží. Use this guide to compare Ancona and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Ancona, Via Einaudi Luigi / Via del Lavoro ( Port) is 1 km from Ancona city centre. Public transport options include:
Ancona, Via Einaudi Luigi / Via del Lavoro ( Port) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Ancona, Via Einaudi Luigi / Via del Lavoro ( Port). ATMs are available at Ancona, Via Einaudi Luigi / Via del Lavoro ( Port).
Ticket office support is available at Ancona, Via Einaudi Luigi / Via del Lavoro ( Port).
Available at Ancona, Via Einaudi Luigi / Via del Lavoro ( Port): Parking, Taxis, WC.
Accessibility facilities are available at Ancona, Via Einaudi Luigi / Via del Lavoro ( Port): Basic accessibility features available.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Here are some other resources that might have the information you need