- Must visit
The Alamo Exhibit at the Ralston Family Collections Center
Modern museum gallery displaying Alamo artifacts and interpretation beside the historic mission site. A strong companion visit for understanding the 1836 battle and Texas history.
Cheapest price
$134
Average price
$134
Fastest journey
11 h 30 m
Average duration
11 h 30 m
Buses per day
1
Distance
717 km
The best way to find a cheap bus ticket from Amarillo, TX to San Antonio, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Amarillo, TX to San Antonio, TX will cost around $134 if you buy it on the day, but the cheapest tickets can be found for only $134.
Of the 1 buses that leave Amarillo, TX for San Antonio, TX on Mon, Jun 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jun 22 the direct buses cover the 717 km distance in an average of 11 h 30 m but if you time it right, some buses will get you there in just 11 h 30 m .
On Mon, Jun 22 the slowest buses will take 11 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Amarillo, TX to San Antonio, TX among Omio's users. If you are prioritising price take the bus with prices starting from $71. For those with little time consider booking a flight which can get you there in 4h 59m. The ticket price range depends on the travel mode: a bus costs an average of $71, and a flight costs an average of $178.
Distance: 445 miles (717 km)
Most popular Bus | Flight | Driving |
|---|---|---|
$108 Average price Cheapest | $388 Average price | $103 Average price (fuel + tolls) |
12h 0m Average total duration 11h 30m Onboard + 30m Additional time* | 7h 59m Average total duration Fastest 4h 59m Onboard + 3h 0m Additional time* | 7h 21m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Amarillo, TX to San Antonio, TX:
A bus is $280 (€229) less than a flight for this route with tickets for a flight from Amarillo, TX to San Antonio, TX costing on average $388 (€317).
Other travel options to San Antonio, TX take longer:
Bus takes on average 11h 30m.
You'll arrive about -5h -9m sooner (11h 30m by bus vs 7h 21m by car) and save roughly $-5.19 (€-4.25) compared to fuel and tolls ($108 (€89) vs $103 (€84)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by Greyhound.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:20AM | Arrival Time 06:10PM | Duration 17h50 | Departure days Tue, Wed, Sun | Cheapest price $100 |
Operator Greyhound USA | Departure Time 07:00AM | Arrival Time 06:30PM | Duration 11h30 | Departure days Mon, Tue, Wed, Sun | Cheapest price $66 |
Operator Greyhound | Departure Time 08:05AM | Arrival Time 11:55PM | Duration 15h50 | Departure days Tue, Wed, Sun | Cheapest price $100 |
Operator Greyhound | Departure Time 12:00PM | Arrival Time 11:30PM | Duration 11h30 | Departure days Thu, Fri | Cheapest price $89 |
Operator Greyhound | Departure Time 01:00PM | Arrival Time 12:30AM | Duration 11h30 | Departure days Fri, Sat | Cheapest price $94 |
The table below shows live departures for Amarillo, TX to San Antonio, TX buses for today, Sunday, June 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+![]() | 12:20 AM Amarillo, Multimodal Transfer Sta, TX | 17h50 | 6:10 PM San Antonio, N St Mary's St (Greyhound), TX | 1 transfer | |
![]() | 7:00 AM Amarillo, Multimodal Transfer Sta, TX | 11h30 | 6:30 PM San Antonio, N St Mary's St (Greyhound), TX | 0 transfersDirect | |
· | 8:05 AM Amarillo, Multimodal Transfer Sta, TX | 15h50 | 11:55 PM San Antonio, N St Mary's St (Greyhound), TX | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Amarillo, TX to San Antonio, TX run on average 2 times per day, taking around 11h 30m. Cheap bus tickets for this journey start at $71 (€58) if you book in advance.
There are 1 buses per day. The earliest bus runs at 01:30, the last at 21:45. The fastest bus covers the 445 miles (717 km) distance in 11h 30m.
Distance 445 miles (717 km) |
Average bus duration 11h 30m |
Cheapest ticket price $71 (€58) |
Buses per day 2 |
Direct buses 1 |
Fastest bus 11h 30m |
First bus 1:30 AM |
Last bus 9:45 PM |
Cheapest Month Oct |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jul - Sep |
Best time to book 49 days |
Discover the best of San Antonio — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Antonio trip today.
Modern museum gallery displaying Alamo artifacts and interpretation beside the historic mission site. A strong companion visit for understanding the 1836 battle and Texas history.
Major art museum with collections spanning ancient Mediterranean works, Asian art, Latin American art, and contemporary pieces in a historic brewery complex.
Leading regional museum focused on Texas history, natural science, and South Texas heritage, with engaging family-friendly exhibits and strong local context.
The city’s signature pedestrian waterfront lined with bridges, public art, and walking paths. It is the most recognizable area in San Antonio.
Large public square and cultural district known for Mexican-American heritage, shops, events, and festive open-air atmosphere.
Trendy mixed-use district in a former brewery area, popular for architecture, river access, and stylish public spaces.
A San Antonio specialty made with freshly fried, puffed corn tortilla shells filled with picadillo, chicken, or beans, then topped with lettuce, cheese, and salsa.
Slow-cooked beef, traditionally served very tender on weekends in tacos with onion, cilantro, and salsa. It is one of the city’s most beloved breakfast foods.
A daily staple in San Antonio, usually made with flour or corn tortillas filled with eggs, beans, potato, bacon, chorizo, or cheese.
Well-regarded upscale restaurant serving refined New American cuisine in a stylish yet relaxed setting south of Downtown.
Popular casual spot famous for oversized breakfast tacos, donuts, and classic San Antonio morning fare.
Iconic Market Square institution known for classic Tex-Mex, bakery items, mariachi atmosphere, and colorful decor.
Generally moderate for U.S. city travel. Budget eats are easy to find, while hotels and attractions vary by season and area.
Tip 18-20% at sit-down restaurants; 20%+ for great service. Tip USD 1-2 per drink at bars, round up or tip 10-15% for taxis, and tip hotel staff a few USD.
Find answers to the most common questions about traveling from Amarillo, TX to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.

Most Amarillo, TX to San Antonio, TX buses use the Amarillo, Multimodal Transfer Sta to San Antonio, N St Mary's St (Greyhound) station pair. Use this guide to compare Amarillo, TX and San Antonio, TX bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need