- Must visit
San Antonio Museum of Art
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
The best way to find a cheap bus ticket from Amarillo, TX to San Antonio, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Amarillo, TX to San Antonio, TX will cost around $87 if you buy it on the day, but the cheapest tickets can be found for only $87.
On Thu, Nov 05, we found 1 buses from Amarillo, TX to San Antonio, TX, including 1 direct services.
On Thu, Nov 05 the direct buses cover the 717 km distance in an average of 11 h 30 m but if you time it right, some buses will get you there in just 11 h 30 m .
On Thu, Nov 05 the slowest buses will take 11 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Amarillo, TX to San Antonio, TX run on average 3 times per day, taking around 13h 29m. Cheap bus tickets for this journey start at $52 if you book in advance.
There are 1 buses per day. The earliest bus runs at 01:30, the last at 21:45. The fastest bus covers the 445 miles (717 km) distance in 11h 30m.
Distance 445 miles (717 km) |
Average bus duration 13h 29m |
Cheapest ticket price $52 |
Buses per day 3 |
Direct buses 1 |
Fastest bus 11h 30m |
First bus 1:30 AM |
Last bus 9:45 PM |
Cheapest Month Sep |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Best time to book 49 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Amarillo, TX to San Antonio, TX.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:20AM | Arrival Time 06:10PM | Duration 17h50 | Departure days Wed | Cheapest price $166 |
Operator Greyhound USA | Departure Time 07:00AM | Arrival Time 06:30PM | Duration 11h30 | Departure days Mon, Wed, Fri | Cheapest price $66 |
Operator Greyhound | Departure Time 08:05AM | Arrival Time 12:05AM | Duration 16h00 | Departure days Wed, Fri | Cheapest price $100 |
Operator Greyhound | Departure Time 12:00PM | Arrival Time 11:30PM | Duration 11h30 | Departure days Tue, Thu, Sun | Cheapest price $87 |
Operator Greyhound | Departure Time 01:00PM | Arrival Time 12:30AM | Duration 11h30 | Departure days Sat | Cheapest price $92 |
The table below shows live departures for Amarillo, TX to San Antonio, TX buses for today, Wednesday, November 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+![]() | 12:20 AM Amarillo, Multimodal Transfer Sta, TX | 17h50 | 6:10 PM San Antonio, N St Mary's St (Greyhound), TX | 1 transfer | |
![]() | 7:00 AM Amarillo, Multimodal Transfer Sta, TX | 11h30 | 6:30 PM San Antonio, N St Mary's St (Greyhound), TX | 0 transfersDirect | |
· | 8:05 AM Amarillo, Multimodal Transfer Sta, TX | 16h00 | 12:05 AM San Antonio, N St Mary's St (Greyhound), TX | 1 transfer | |
This is the last bus of the day. | |||||
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Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of San Antonio, TX — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Antonio, TX trip today.
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
This leading Latinx art museum showcases contemporary and historic works, making it one of the city’s most distinctive cultural stops.
Housed in a former brewery, this contemporary art museum presents rotating exhibitions in one of San Antonio’s most atmospheric spaces.
The city’s signature pedestrian corridor links shops, boats, bridges, and historic architecture, making it San Antonio’s essential walking experience.
This artsy, fast-evolving district mixes galleries, murals, boutiques, and nightlife with a strong local identity near the river.
A lively downtown plaza framed by major civic buildings, it is best known for events, fountains, and the nightly cathedral light show nearby.
Puffy tacos are San Antonio’s signature dish: crisp, airy fried corn tortillas filled with picadillo, chicken, or beans, rooted in local Tex-Mex history.
Barbacoa is slow-cooked beef, often served on weekends in breakfast tacos. It is a beloved South Texas tradition with deep Mexican roots.
Breakfast tacos are a daily staple in San Antonio, usually filled with egg, potato, bean, bacon, or chorizo in flour or corn tortillas.
Refined River Walk restaurant serving upscale South Texas and Mexican cuisine. Elegant atmosphere with a long-standing fine dining reputation.
Popular breakfast and lunch spot known for house-made tortillas, tacos, and classic San Antonio Tex-Mex in a relaxed setting.
Beloved market restaurant for authentic Mexican dishes, fresh tortillas, and bakery items. Bustling, traditional atmosphere.
Moderate for a major U.S. city. Hotels and dining are usually cheaper than New York or San Francisco, while car use can add costs because transit is limited.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-$2 per drink or coffee if there is table or bar service.
Official public transport app
UTSA East Campus Lot 1 -> Downtown San Antonio
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in San Antonio, TX.
Find answers to the most common questions about traveling from Amarillo, TX to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.

Most Amarillo, TX to San Antonio, TX buses use the Amarillo, Multimodal Transfer Sta to San Antonio, N St Mary's St (Greyhound) station pair. Use this guide to compare Amarillo, TX and San Antonio, TX bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Amarillo, Multimodal Transfer Sta is 2 km from Amarillo city centre. Public transport options include:
Amarillo, Multimodal Transfer Sta has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free public Wi-Fi available. ATMs are available at Amarillo, Multimodal Transfer Sta.
Ticket office support is available at Amarillo, Multimodal Transfer Sta.
Available at Amarillo, Multimodal Transfer Sta: Parking, Taxis, WC.
Accessibility facilities are available at Amarillo, Multimodal Transfer Sta: Wheelchair accessible entrances and pathways.
San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).
Ticket office support is available at San Antonio, N St Mary's St (Greyhound).
Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.
Check bus stations information for Amarillo, TX and San Antonio, TX, including where buses depart and arrive on this route.
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