Travel Information
Compare train, bus, and flight for San Donato Milanese to Naples
Omio recommends booking the bus as it is the most popular option from San Donato Milanese to Naples among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $54 For those with little time, consider booking a flight, which has an average total journey time of 4h 31m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.6kg. Average ticket prices depend on the travel mode: a bus costs an average of $54, while a flight costs an average of $423.
Distance: 404 miles (651 km)
Compare bus with
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$54 Average price Cheapest | $423 Average price | $102 Average price | $226 Average price (fuel + tolls) |
11h 6m Average total duration 10h 36m Onboard + 30m Additional time* | 4h 31m Average total duration Fastest 2h 31m Onboard + 2h 0m Additional time* | 7h 24m Average total duration 6h 54m Onboard + 30m Additional time* | 7h 13m Average total duration (door-to-door) |
0.7 - 1.6kg CO2 emissions | - CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from San Donato Milanese to Naples
Compare the available ways to get from San Donato Milanese to Naples, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from San Donato Milanese to Naples:
A bus is $48 (€41) less than a train for this route with tickets for a train from San Donato Milanese to Naples costing on average $102 (€86).
A bus is $369 (€310) less than a flight for this route with tickets for a flight from San Donato Milanese to Naples costing on average $423 (€355).
Other travel options to Naples take longer:
Train takes on average 7h 24m.
Bus takes on average 11h 6m.
Tickets start at around $54 (€45) compared to roughly $226 (€190) in fuel and tolls — a saving of about $172 (€145). The journey takes 10h 36m versus 7h 13m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom San Donato Milanese to Naples
How to get from San Donato Milanese to Naples by train, bus or flight.
Our recommendation
The best way to travel from San Donato Milanese to Naples is by taking a bus because it’s the best combination of price and speed.
FlixBus12:45 PM 10h45 Milano, San Donato - Settore B (Viale Giuseppe Impastato) 11:30 PM Naples, Metropark Centrale(Terminal Bus FS Park) $25 1 One-way 0 transfers
Cheapest
FlixBus12:45 PM 10h45 Milano, San Donato - Settore B (Viale Giuseppe Impastato) 11:30 PM Naples, Metropark Centrale(Terminal Bus FS Park) $25 1 One-way 0 transfers
Fastest
FlixBus · FlixBus9:05 PM 9h15 Milano, San Donato - Settore B (Viale Giuseppe Impastato) 6:20 AM Naples, Metropark Centrale(Terminal Bus FS Park) $78 1 One-way 1 transfer
Other options
S1 TRENORD 24143+
Intercity 5971:40 PM 9h54 San Donato Milanese station 11:34 PM Naples Centrale $92 1 One-way 1 transfer
S1 TRENORD 24111+
Intercity 5835:40 AM 10h05 San Donato Milanese station 3:45 PM Naples Centrale $92 1 One-way 1 transfer
S1 TRENORD 24122 · Regionale Veloce 3017+
Intercity 5118:21 AM 12h08 San Donato Milanese station 8:29 PM Naples Centrale $95 1 One-way 2 transfers
FlixBus8:50 AM 10h25 Milano, San Donato - Settore B (Viale Giuseppe Impastato) 7:15 PM Naples, Metropark Centrale(Terminal Bus FS Park) $27 1 One-way 0 transfers
FlixBus1:10 AM 10h35 Milano, San Donato - Settore B (Viale Giuseppe Impastato) 11:45 AM Naples, Metropark Centrale(Terminal Bus FS Park) $33 1 One-way 0 transfers
24219:35 PM 11h10 Milano, San Donato - Settore B (Viale Giuseppe Impastato) 8:45 AM Napoli, Autostazione Metropark $36 1 One-way 0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from San Donato Milanese to Naples
Travel to Naples easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from San Donato Milanese to Naples.

This is compared to other travel options from San Donato Milanese to Naples:
A bus is $48 (€41) less than a train for this route with tickets for a train from San Donato Milanese to Naples costing on average $102 (€86).
A bus is $369 (€310) less than a flight for this route with tickets for a flight from San Donato Milanese to Naples costing on average $423 (€355).
Other travel options to Naples take longer:
Train takes on average 7h 24m.
Bus takes on average 11h 6m.
- Around 24 flights per day.
- Around 18 buses per day.
- Around 8 trains per day.
However, we recommend checking specific travel dates for your route between San Donato Milanese and Naples as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Milan Linate Airport and arrive in Naples International Airport.
- Trains mostly depart from Milan Rogoredo and arrive in Naples Centrale.
- Buses mostly depart from Milano, San Donato - Settore B (Viale Giuseppe Impastato) and arrive in Naples, Metropark Centrale(Terminal Bus FS Park).
- Travel with Italo, Intercity, Frecciarossa, Intercity Notte to go to Naples by train.
- Travel with ITA, British Airways, Malta Air, easyJet, Ryanair, Volotea, Eurowings, Neos Air, Avion Express Malta to go to Naples by flight.
- Travel with FlixBus, Itabus, Marino Autolinee, Salemi to go to Naples by bus.
- 5 direct trains per day with Italo, Frecciarossa.
- 9 direct flights per day with ITA, Malta Air, easyJet, Ryanair, Volotea, Neos Air.
- 9 direct buses per day with FlixBus, Itabus, Marino Autolinee, Salemi.
Travelling from San Donato Milanese to Naples: related information
Here are some other resources that might have the information you need


