Travel Information
Compare train, bus, and flight for Antwerp to Madrid
Omio recommends booking the bus as it is the most popular option from Antwerp to Madrid among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €140 For those with little time, consider booking a flight, which has an average total journey time of 6h 14m. Average ticket prices depend on the travel mode: a bus costs an average of €140, while a flight costs an average of €446.
Distance: 841 miles (1354 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
€140 Average price Cheapest | €446 Average price | €382 Average price (fuel + tolls) |
23h 41m Average total duration 23h 11m Onboard + 30m Additional time* | 6h 14m Average total duration Fastest 4h 14m Onboard + 2h 0m Additional time* | 16h 12m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Antwerp to Madrid:
A bus is €306 less than a flight for this route with tickets for a flight from Antwerp to Madrid costing on average €446.
Other travel options to Madrid take longer:
Bus takes on average 23h 41m.
Tickets start at around €140 compared to roughly €382 in fuel and tolls — a saving of about €243. The journey takes 23h 11m versus 16h 12m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Antwerp to Madrid
How to get from Antwerp to Madrid by train, bus or flight.
Our recommendation
The best way to travel from Antwerp to Madrid is by taking a bus because it’s the best combination of price and speed.
1658 · 31634:05 PM23h05Antwerp, Van Ertbornstraat (Rooseveltplaats)3:10 PMMadrid, Estación Sur de Autobuses€621One-way1 transfer
Cheapest
1658 · 31634:05 PM23h05Antwerp, Van Ertbornstraat (Rooseveltplaats)3:10 PMMadrid, Estación Sur de Autobuses€621One-way1 transfer
Fastest
FR 53778:45 AM2h25Brussels South Charleroi Airport11:10 AMMadrid Barajas Airport€3931One-way0 transfers
Other options
83133 · 31633:40 PM23h30Antwerpen, P+R Luchtbal3:10 PMMadrid, Estación Sur de Autobuses€621One-way1 transfer
1646 · 400311:30 AM25h45Antwerpen, P+R Luchtbal1:15 PMMadrid, Estación Sur de Autobuses€671One-way1 transfer
51122 · 400311:50 AM25h25Antwerpen, Borsbeeksebrug (Berchem)1:15 PMMadrid, Estación Sur de Autobuses€721One-way1 transfer
UX11746:55 PM2h30Brussels Airport9:25 PMMadrid Barajas Airport€1851One-way0 transfers
9937+
IB7342:00 PM8h10Antwerp-Central10:10 PMMadrid Barajas Airport€2181One-way1 transfer
9439+
IB7342:30 PM7h40Antwerp-Central10:10 PMMadrid Barajas Airport€2281One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Antwerp to Madrid
Travel to Madrid easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Antwerp to Madrid.

This is compared to other travel options from Antwerp to Madrid:
A bus is €306 less than a flight for this route with tickets for a flight from Antwerp to Madrid costing on average €446.
Other travel options to Madrid take longer:
Bus takes on average 23h 41m.
- Around 86 flights per day.
- Around 15 buses per day.
However, we recommend checking specific travel dates for your route between Antwerp and Madrid as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Brussels Airport and arrive in Madrid Barajas Airport.
- Buses mostly depart from Antwerp, Van Ertbornstraat (Rooseveltplaats) and arrive in Madrid, Estación Sur de Autobuses.
- Travel with Ryanair, Iberia, Eurowings, Lufthansa City Airlines, Brussels Airlines, Air Europa, KLM Cityhopper, BA Cityflyer, Qatar Airways, Avion Express Malta, Air Baltic, Helvetic Airways, Lot Polish Airlines, British Airways, Swiss, Air France, KLM, Lufthansa, Vueling, Royal Air Maroc, Smartwings, Turkish Airlines, ITA, TAP Portugal, Tuifly to go to Madrid by flight.
- Travel with BlaBlaCar Bus, FlixBus to go to Madrid by bus.
- 13 direct flights per day with Ryanair, Iberia, Eurowings, Brussels Airlines, Air Europa, Avion Express Malta, Air Baltic.
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