Compare prices and tickets Frankfurt South station to Mainz Hbf by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Frankfurt South station to Mainz Hbf trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of FlixTrain or Deutsche Bahn Regio (DB Regional) to find the best option for your trip from Frankfurt South station to Mainz Hbf.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are train and bus to ensure you get the best deal for traveling from Frankfurt South station to Mainz Hbf.
Why book with Omio over Trainline or Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Frankfurt South station to Mainz Hbf.
Journey information
Overview: Train from Frankfurt South station to Mainz Hbf
Trains from Frankfurt South station to Mainz Hbf run on average 1 times per day, taking around 38m. Cheap train tickets for this journey start at $22 (€17) if you book in advance.
The earliest train runs at 05:27, the last at 05:27. The fastest train covers the 19 miles (32 km) distance in 48m.
Distance 19 miles (32 km) |
Average train duration 38m |
Cheapest ticket price $22 (€17) |
Trains per day 1 |
Fastest train 48m |
First train 05:27 |
Last train 05:27 |
Train companies: Deutsche Bahn, FlixTrain, Deutsche Bahn Regio (DB Regional) from Frankfurt South station to Mainz Hbf trainsDeutsche Bahn, FlixTrain, Deutsche Bahn Regio (DB Regional) trains will get you between Frankfurt South station and Mainz Hbf from $22 (€17). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
FlixTrain
Deutsche Bahn Regio (DB Regional)
FAQs: Trains from Frankfurt South station to Mainz Hbf
Find answers to the most common questions about traveling from Frankfurt South station to Mainz Hbf by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Mainz Hbf, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Frankfurt South station to Mainz Hbf
- Merals Imbiss
- Bootshaus am Eisernen Steg
- Freigut
- Holbein's
- Hotel am Berg
- Leonardo Royal Hotel Frankfurt
- Hotel Ritter
- Lindner Main Plaza
- Monday: 06:00 - 21:15
- Tuesday: 06:00 - 21:15
- Wednesday: 06:00 - 21:15
- Thursday: 06:00 - 21:15
- Friday: 06:00 - 21:15
- Saturday: 07:00 - 19:00
- Sunday: 08:00 - 20:00
- Mangal
- Asia Wok
- Bistrorante Midi
- McDonald's
- Advena Europa Hotel
- GuestHouse Mainz
- Terminus
- Hotel Moguntia
Most popular train connections from Frankfurt South station
More options for your journey from Frankfurt South station to Mainz Hbf
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