Journey information
Overview: Santiago to Antofagasta flight
Flights from Santiago to Antofagasta depart on average 23 times per day, taking around 3h 11m. Cheap flight tickets for this journey start at €26 if you book in advance.
There are 15 flights per day. The earliest flight runs at 00:09, the last at 23:58. The fastest flight covers the 677 miles (1091 km) distance in 1h 58m. October is the cheapest month to fly.
Distance 677 miles (1091 km) |
Average flight duration 3h 11m |
Cheapest ticket price €26 |
Flights per day 23 |
Direct flights 15 |
Fastest flight 1h 58m |
First flight 12:09 AM |
Last flight 11:58 PM |
Cheapest Month Oct |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 21 days |
The cheapest and fastest flights from Santiago to Antofagasta
Cheapest price on Sep 17
€38
Average ticket price on Sep 17
€127
Fastest journey on Sep 17
2 h 2 m
Average journey duration on Sep 17
2 h 2 m
Flights on Sep 17
29
Distance
1091 km
The best way to find a cheap flight ticket from Santiago to Antofagasta is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santiago to Antofagasta will cost around €127 if you buy it on the day, but the cheapest tickets can be found for only €38.
On Thu, Sep 17, we found 29 flights from Santiago to Antofagasta, including 22 direct services.
On Thu, Sep 17 the direct flights cover the 1091 km distance in an average of 2 h 2 m but if you time it right, some flights will get you there in just 2 h 2 m .
On Thu, Sep 17 the longest flights will take 2 h 3 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
645:19 AM2h05Santiago7:24 AMAntofagasta€381One-way0 transfers
524:20 AM2h05Santiago6:25 AMAntofagasta€381One-way0 transfers
H22706:00 AM2h02Santiago8:02 AMAntofagasta€411One-way0 transfers
H22742:02 PM2h02Santiago4:04 PMAntofagasta€411One-way0 transfers
H212783:30 PM2h02Santiago5:32 PMAntofagasta€411One-way0 transfers
H22706:00 AM2h02Santiago8:02 AMAntofagasta€411One-way0 transfers
H22742:02 PM2h02Santiago4:04 PMAntofagasta€411One-way0 transfers
H212783:30 PM2h02Santiago5:32 PMAntofagasta€411One-way0 transfers
H22967:40 PM2h02Santiago9:42 PMAntofagasta€591One-way0 transfers
LA3465:00 PM2h03Santiago7:03 PMAntofagasta€551One-way0 transfers
Travel Information
Compare bus and flight for Santiago to Antofagasta
Omio recommends booking the flight as it is the most popular option from Santiago to Antofagasta among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €39 For those with little time, consider booking a flight, which has an average total journey time of 5h 11m. Average ticket prices depend on the travel mode: a bus costs an average of €39, while a flight costs an average of €262.
Distance: 677 miles (1091 km)
Compare flight with
Most popular Flight | Bus | Driving |
|---|---|---|
€262 Average price | €39 Average price Cheapest | €179 Average price (fuel + tolls) |
5h 11m Average total duration Fastest 3h 11m Onboard + 2h 0m Additional time* | 18h 21m Average total duration 17h 51m Onboard + 30m Additional time* | 14h 44m Average total duration (door-to-door) |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Santiago to Antofagasta:
A bus is €223 less than a flight for this route with tickets for a flight from Santiago to Antofagasta costing on average €262.
Other travel options to Antofagasta take longer:
Bus takes on average 17h 51m.
Live departures
Santiago to Antofagasta flight times
The table below shows live departures for Santiago to Antofagasta flights for tomorrow, Thursday, September 17. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
52 | 4:20 AM Santiago | 2h05 | 6:25 AM Antofagasta | 0 transfersDirect | |
LA146 · LA395 · LA368 | 5:02 AM Santiago | 12h06 | 5:08 PM Antofagasta | 2 transfers | |
LA122 | 5:10 AM Santiago | 2h04 | 7:14 AM Antofagasta | 0 transfersDirect | |
64 | 5:19 AM Santiago | 2h05 | 7:24 AM Antofagasta | 0 transfersDirect | |
H2270 | 6:00 AM Santiago | 2h02 | 8:02 AM Antofagasta | 0 transfersDirect | |
LA100 · LA368 | 6:00 AM Santiago | 11h08 | 5:08 PM Antofagasta | 1 transfer | |
LA148 · LA395 · LA368 | 6:01 AM Santiago | 11h07 | 5:08 PM Antofagasta | 2 transfers | |
LA124 | 6:03 AM Santiago | 2h04 | 8:07 AM Antofagasta | 0 transfersDirect | |
LA150 · LA395 · LA368 | 6:31 AM Santiago | 10h37 | 5:08 PM Antofagasta | 2 transfers | |
LA128 | 6:57 AM Santiago | 2h04 | 9:01 AM Antofagasta | 0 transfersDirect | |
60 | 6:59 AM Santiago | 2h05 | 9:04 AM Antofagasta | 0 transfersDirect | |
1210 · 1714 | 9:00 AM Santiago | 9h42 | 6:42 PM Antofagasta | 1 transfer | |
LA348 | 9:53 AM Santiago | 2h04 | 11:57 AM Antofagasta | 0 transfersDirect | |
LA106 · LA368 | 10:04 AM Santiago | 7h04 | 5:08 PM Antofagasta | 1 transfer | |
LA374 · LA395 · LA368 | 10:23 AM Santiago | 6h45 | 5:08 PM Antofagasta | 2 transfers | |
LA134 | 10:53 AM Santiago | 2h04 | 12:57 PM Antofagasta | 0 transfersDirect | |
LA132 | 11:43 AM Santiago | 2h04 | 1:47 PM Antofagasta | 0 transfersDirect | |
LA136 | 12:17 PM Santiago | 2h04 | 2:21 PM Antofagasta | 0 transfersDirect | |
LA354 | 12:44 PM Santiago | 2h04 | 2:48 PM Antofagasta | 0 transfersDirect | |
LA130 | 1:32 PM Santiago | 2h04 | 3:36 PM Antofagasta | 0 transfersDirect | |
H2274 | 2:02 PM Santiago | 2h02 | 4:04 PM Antofagasta | 0 transfersDirect | |
H21714 | 3:24 PM Santiago | 3h18 | 6:42 PM Antofagasta | 0 transfersDirect | |
H21278 | 3:30 PM Santiago | 2h02 | 5:32 PM Antofagasta | 0 transfersDirect | |
LA340 | 3:33 PM Santiago | 2h03 | 5:36 PM Antofagasta | 0 transfersDirect | |
LA346 | 5:00 PM Santiago | 2h03 | 7:03 PM Antofagasta | 0 transfersDirect | |
LA1850 | 5:20 PM Santiago | 2h03 | 7:23 PM Antofagasta | 0 transfersDirect | |
LA342 | 6:10 PM Santiago | 2h03 | 8:13 PM Antofagasta | 0 transfersDirect | |
H2296 | 7:40 PM Santiago | 2h02 | 9:42 PM Antofagasta | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santiago to Antofagasta by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sep 17
Sep 18
Sep 19
Sep 20
Sep 21
Sep 22
Sep 23
Why should you book Santiago to Antofagasta flights with Omio?
Why book with Omio vs jetsmart?
- Compare with other providers: On Omio, you can not only buy tickets for jetsmart, but also compare tickets for the likes of Latam Airlines, Sky Airline or CitizenPlane to find the best option for your trip from Santiago to Antofagasta.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare jetsmart with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Santiago to Antofagasta.
Why book with Omio over Edreams, Kayak or Skyscanner?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Latam Airlines, Sky Airline or CitizenPlane to find the best option for your trip from Santiago to Antofagasta.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Santiago to Antofagasta.
Airlines: Latam Airlines, Sky Airline, jetsmart, CitizenPlane from Santiago to AntofagastaFind the best flights between Santiago to Antofagasta with Omio's travel partners Latam Airlines, Sky Airline, jetsmart, CitizenPlane from €26. We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Latam Airlines
Sky Airline
jetsmart
CitizenPlane
FAQs: Santiago to Antofagasta Flight
Find answers to the most common questions about traveling from Santiago to Antofagasta by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Antofagasta, this guide helps you travel smarter and with confidence.

popular airports
Popular airports from Santiago to Antofagasta
Most Santiago to Antofagasta flights use the Santiago to Antofagasta airport pair. Use this guide to compare Santiago and Antofagasta airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Which Santiago airport do flights to Antofagasta leave from?
Getting to Santiago from Santiago city centre
Santiago is 8 km from Santiago city centre. Public transport options include:
Santiago airport facilities and services
Santiago has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food and drink
Food options include: Restaurants available in both domestic and intertiol terminals; options include fast food and Chilean cuisine.
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are located in both domestic and intertiol terminals.
Luggage and lost property
Lost and found is available at the station.
Parking, taxis and toilets
Available at Santiago: Parking, Taxis, WC.
Bike and car services
Available at Santiago: Car Rental.
Accessibility
Accessibility facilities are available at Santiago: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Hotels nearby include Holiday Inn Santiago Airport, within walking distance..
Which Antofagasta airport do flights from Santiago arrive at?
Getting to Antofagasta from Antofagasta city centre
Antofagasta is 23 km from Antofagasta city centre. Public transport options include:
Antofagasta airport facilities and services
Antofagasta has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Lounge, Lost and Found Office, and Car Rental.
Food and drink
Food options include: Several restaurants and cafes are located in the main terminal, offering local and intertiol cuisine.
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are located in the arrivals and departures areas.
Luggage and lost property
Lost and found is available at the station.
Parking, taxis and toilets
Available at Antofagasta: Parking, Taxis, WC.
Bike and car services
Available at Antofagasta: Car Rental.
Accessibility
Accessibility facilities are available at Antofagasta: Elevators, ramps.
More options for your journey from Santiago to Antofagasta
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