Journey information
Overview: Portland, ME to Frederick, MD flight
Take a flight from Portland, ME to Frederick, MD and enjoy the approximately 472 miles (760 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest flight runs at 05:40, the last at 12:29.
Distance 472 miles (760 km) |
Average flight duration 1h 52m |
First flight 05:40 |
Last flight 12:29 |
Why should you book Portland, ME to Frederick, MD flights with Omio?
Why book with Omio vs American Airlines?
- Compare with other providers: On Omio, you can not only buy tickets for American Airlines, but also compare tickets for the likes of Republic Airlines to find the best option for your trip from Portland, ME to Frederick, MD.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Airlines: American Airlines, Republic Airlines from Portland, ME to Frederick, MDFind the best flights between Portland, ME to Frederick, MD with Omio's travel partners American Airlines, Republic Airlines. We can find you the best deals, schedules and tickets when comparing and booking the best trip.
American Airlines
Republic Airlines
FAQs: Portland, ME to Frederick, MD Flight
Find answers to the most common questions about traveling from Portland, ME to Frederick, MD by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Frederick, MD, this guide helps you travel smarter and with confidence.

- National Apple Harvest Festival, a vibrant celebration of the apple harvest featuring local crafts, food vendors, and live entertainment
- Frederick Wine Festival, an annual event showcasing local wineries with tastings, food pairings, and live music
- In the Street Festival, a lively street fair with arts and crafts vendors, live performances, and family-friendly activities.
- Memorial Day, the unofficial start of summer with vibrant outdoor activities and events
- Independence Day, spectacular fireworks and festive celebrations throughout the city
- Labor Day, a great time for enjoying local festivals and pleasant weather before fall.
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