- Must visit
Museo Nacional de Bellas Artes
Chile's leading fine arts museum in a landmark 1910 palace. Visit for national and international art plus one of the city's most beautiful interiors.
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Journey information
Overview: La Serena to Santiago flight
ChileChile
Flights from La Serena to Santiago depart on average 7 times per day, taking around 2h 15m. Cheap flight tickets for this journey start at $36 (€29) but you can travel from only $14 (€12) by bus.
There are 7 flights per day. The earliest flight runs at 04:50, the last at 22:25. The fastest flight covers the 247 miles (399 km) distance in 56m. June is the cheapest month to fly.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $14 (€12)
Distance 247 miles (399 km) |
Average flight duration 2h 15m |
Cheapest ticket price $36 (€29) |
Flights per day 7 |
Direct flights 7 |
Fastest flight 56m |
First flight 4:50 AM |
Last flight 10:25 PM |
Cheapest Month Jun |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Apr - Jun |
Busiest Day Sun |
Least Busy Day Thu |
Best time to book 1 day |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $14 (€12)
The cheapest and fastest flights from La Serena to Santiago
Showing times, prices and bookable tickets for Aug 30
Cheapest price on Aug 30
$40
Average ticket price on Aug 30
$93
Fastest journey on Aug 30
55 m
Average journey duration on Aug 30
57 m
Flights on Aug 30
7
Distance
399 km
Cheap tickets
The best way to find a cheap flight ticket from La Serena to Santiago is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from La Serena to Santiago will cost around $93 if you buy it on the day, but the cheapest tickets can be found for only $40.
Fast flights
On Sun, Aug 30, we found 7 flights from La Serena to Santiago, including 7 direct services.
On Sun, Aug 30 the direct flights cover the 399 km distance in an average of 57 m but if you time it right, some flights will get you there in just 55 m .
On Sun, Aug 30 the longest flights will take 59 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
4:43 PM0h58La Serena5:41 PMSantiago$401One-way0 transfers
7:55 PM1h00La Serena8:55 PMSantiago$591One-way0 transfers- 7:45 PM0h59La Serena8:44 PMSantiago$821One-way0 transfers
- 7:15 PM0h59La Serena8:14 PMSantiago$871One-way0 transfers
4:22 PM0h55La Serena5:17 PMSantiago$1061One-way0 transfers
- 4:22 PM0h55La Serena5:17 PMSantiago$1061One-way0 transfers
- 1:40 PM0h55La Serena2:35 PMSantiago$1551One-way0 transfers
- 4:43 PM0h58La Serena5:41 PMSantiago$401One-way0 transfers
- 3:35 PM0h59La Serena4:34 PMSantiago$1211One-way0 transfers
- 7:45 PM0h59La Serena8:44 PMSantiago$821One-way0 transfers
Travel Information
Compare bus and flight for La Serena to Santiago
Omio recommends booking the bus as it is the most popular option from La Serena to Santiago among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $21 For those with little time, consider booking a bus, which has an average total journey time of 4h 4m. Average ticket prices depend on the travel mode: a bus costs an average of $21, while a flight costs an average of $45.
Distance: 247 miles (399 km)
Compare flight with
| Flight | Most popular Bus | Driving |
|---|---|---|
$45 Average price | $21 Average price Cheapest | $90 Average price (fuel + tolls) |
4h 15m Average total duration 2h 15m Onboard + 2h 0m Additional time* | 4h 4m Average total duration Fastest 3h 34m Onboard + 30m Additional time* | 5h 25m Average total duration (door-to-door) |
Most popular airline |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from La Serena to Santiago is a bus with an average price of $21 (€17).
This is compared to other travel options from La Serena to Santiago:
A bus is $24 (€20) less than a flight for this route with tickets for a flight from La Serena to Santiago costing on average $45 (€36).
The fastest way to travel from La Serena to Santiago is by flight with an average journey time of 2h 15m.
Other travel options to Santiago take longer:
Bus takes on average 3h 34m.
It's helpful to compare your options as there are 2 ways to travel between La Serena and Santiago including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from La Serena to Santiago among Omio's users.
Live departures
La Serena to Santiago flight times
The table below shows live departures for La Serena to Santiago flights for today, Saturday, August 29. You can also manually refresh the results below to see updated flight journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 12:45 PM La Serena | 0h59 | 1:44 PM Santiago | 0 transfersDirect | |
| 2:38 PM La Serena | 1h00 | 3:38 PM Santiago | 0 transfersDirect | |
| 3:41 PM La Serena | 0h59 | 4:40 PM Santiago | 0 transfersDirect | |
| 10:36 PM La Serena | 1h00 | 11:36 PM Santiago | 0 transfersDirect | |
| 10:55 PM La Serena | 0h59 | 11:54 PM Santiago | 0 transfersDirect |
Find all the dates and times for this journey
Compare prices and tickets La Serena to Santiago by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sun
Aug 30
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Why should you book La Serena to Santiago flights with Omio?
jetsmart as well as Latam Airlines or Sky Airline offer flights services from La Serena to Santiago.
Omio is an official ticket reseller for all your travel options from La Serena to Santiago.
Why book with Omio vs jetsmart?
- Compare with other providers: On Omio, you can not only buy tickets for jetsmart, but also compare tickets for the likes of Latam Airlines or Sky Airline to find the best option for your trip from La Serena to Santiago.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare jetsmart with all available travel options, which are bus and flight to ensure you get the best deal for traveling from La Serena to Santiago.
Why book with Omio over Edreams, Kayak or Skyscanner?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Latam Airlines or Sky Airline to find the best option for your trip from La Serena to Santiago.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from La Serena to Santiago.
Airlines: jetsmart, Latam Airlines, Sky Airline from La Serena to SantiagoFind the best flights between La Serena to Santiago with Omio's travel partners jetsmart, Latam Airlines, Sky Airline from $14 (€12). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Latam Airlines
About
LATAM Airlines Peru, a subsidiary of LATAM Airlines Group, is a major airline based in Lima, Peru, and the dominant carrier in the Peruvian domestic market. It operates scheduled domestic and international flights, with its main hub at Jorge Chávez International Airport. The airline was formerly known as LAN Perú S.A. until 2015, when it was dissolved and rebranded as LATAM Airlines as part of the merger between LAN Airlines and TAM Airlines. LATAM Airlines Group, the parent company, is the largest airline group in South America.
Luggage & cancellation policy
Average Latam Airlines Duration
56m
Cheapest Latam Airlines Price
$55 (€44)
Latam Airlines frequency
5 a day
Luggage included
1 carry-on bag (max 10kg) and 1 personal item
Additional luggage
Additional checked baggage can be purchased, up to 23kg per piece
Cancellation Policy
Free cancellation within 24 hours of booking, after that fees apply based on fare type and timing
Pregnant on board
Up to 32 weeks for single pregnancy, 28 weeks for multiple. Medical certificate required after 28 weeks
Unaccompagned minor
Children aged 5-17 can travel alone with LATAM's Unaccompanied Minor service. Service must be requested at least 48 hours before flight
Amenities on board the airplane
Wifi
USB plugs
Accessibility
Assistance available for passengers with reduced mobility, including wheelchairs and special assistance
Pets
Small pets allowed in cabin, max 8kg including carrier. Must be booked in advance
Entertaiment on board
Sky Airline
Luggage & cancellation policy
Average Sky Airline Duration
1h 1m
Cheapest Sky Airline Price
$36 (€29)
Sky Airline frequency
2 a day
Luggage included
1 carry-on bag (45x35x25cm) max 10kg
Additional luggage
23kg checked baggage available for purchase
Cancellation Policy
Free cancellation within 24 hours of booking if flight is more than 7 days away. After that, fees apply based on fare type.
Pregnant on board
Up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required after 28 weeks
Unaccompagned minor
Children aged 5-17 can travel unaccompanied with service fee. Must be requested 48 hours before flight
Amenities on board the airplane
Wifi
USB plugs
Accessibility
Assistance available for passengers with reduced mobility, must be requested 48 hours before flight
Pets
Dogs and cats allowed in cabin and cargo hold, must be in approved carrier
Entertaiment on board
jetsmart
Luggage & cancellation policy
Average jetsmart Duration
1h 0m
Cheapest jetsmart Price
$40 (€32)
jetsmart frequency
1 a day
Luggage included
1 carry-on bag (45x35x25 cm) or personal item (35x25x20 cm)
Additional luggage
Up to 23kg checked baggage can be purchased
Cancellation Policy
Non-refundable tickets, changes allowed with fee depending on fare type
Pregnant on board
Pregnant women can fly up to 28 weeks without medical certificate, between 28-36 weeks require medical certificate, not allowed after 36 weeks
Unaccompagned minor
Children between 5-12 years can travel as unaccompanied minors with additional service fee
Amenities on board the airplane
Accessibility
JetSmart provides assistance for passengers with reduced mobility, including wheelchair services and priority boarding. Passengers are advised to request assistance at least 48 hours before the flight to ensure proper arrangements.
Complete guide to Santiago
Things to do in Santiago
Discover the best of Santiago — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Santiago trip today.
- Must visit
Museo de la Memoria y los Derechos Humanos
Compelling museum on human rights abuses during the dictatorship. Essential for understanding modern Chile through multimedia, testimony, and archives.
- Must visit
Museo Chileno de Arte Precolombino
Interactive pre-Columbian museum in a restored colonial building. Famous for Andean and Mesoamerican collections and clear, engaging interpretation.
- Must visit
Plaza de Armas
Santiago's historic main square, surrounded by key civic and religious buildings. Ideal for architecture, street life, and starting a downtown walk.
- Must visit
Parque Metropolitano de Santiago
Large urban park and hill complex with trails, gardens, pools, and lookouts. A signature Santiago experience for views and open-air recreation.
- Must visit
Lastarria
Leafy cultural district known for mansions, museums, and cafes nearby. Walk here for elegant architecture, galleries, and a relaxed urban atmosphere.
Empanada De Pino
Empanada de pino is Chile’s classic baked pastry filled with beef, onion, egg, olive, and raisins; a staple for fiestas patrias and everyday bakeries.
- Gluten-free
Pastel De Choclo
Pastel de choclo is a baked corn casserole with sweet corn topping over beef or chicken, onion, olives, and egg; a beloved central Chile comfort dish.
- Gluten-free
Cazuela
Cazuela is a traditional homemade broth with beef or chicken, pumpkin, potato, corn, and rice; valued as hearty Chilean family cooking.
Boragó
Refined restaurant in a restored mansion, celebrated for contemporary Chilean cuisine and polished fine dining service.
Fuente Alemana
Traditional Fuente de soda famed for oversized sandwiches, completos, and classic casual Santiago dining.
Liguria
Well-known neighborhood restaurant serving Chilean staples, seafood, and comforting local dishes in a relaxed setting.
Chilean peso ($)
Moderate for South America; hotels cost more than in Lima, but dining and metro stay reasonable for tourists.
Average meal costs
- Budget
- $6.000-$10.000 for fast food or casual lunch.
- Mid-range
- $12.000-$22.000 per person for a meal.
- Fine dining
- $35.000+ per person for upscale restaurants.
- Coffee
- $2.000-$3.500 for cappuccino.
Tipping culture
A 10% restaurant tip is customary and often suggested on the bill. Round up for cafes and taxis; tipping is not expected for short taxi rides.
RED
Get the appOfficial public transport app
Prices
- Single ticket
- $700
- Day pass
- $700
To the city center
Arturo Merino Benítez Airport -> Plaza de Armas, Santiago
- Distance
- 18 km
- Travel time
- 40 min
- Metro and buses in Santiago use the Bip! card. Bank card contactless payment is not generally accepted directly on Metro gates or buses.
- Airport buses connect the airport with Metro stations and the city center. Load enough balance on your Bip! card before peak hours to avoid queues.
FAQs: La Serena to Santiago Flight
Find answers to the most common questions about traveling from La Serena to Santiago by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Santiago, this guide helps you travel smarter and with confidence.
Cheap plane tickets from La Serena to Santiago can start from as little as $36 (€29) when you book in advance. The average flight ticket price for La Serena to Santiago is $45 (€36) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from La Serena to Santiago is 56m to travel the 247 miles (399 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from La Serena to Santiago leaves at 4:50 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from La Serena to Santiago leaves at 10:25 PM.
Yes, there are 7 direct flights a day from La Serena to Santiago with jetsmart, Latam Airlines, Sky Airline. Schedules can vary on holidays or weekends with fewer direct flights.
When taking a flight from La Serena to Santiago, you can count on jetsmart, Latam Airlines, Sky Airline for the best way to get you to Santiago. You can also check all possible airlines who offer a service between La Serena and Santiago and compare the amenities they offer before buying a plane ticket.
Flights from La Serena to Santiago generally leave from La Serena and arrive in Santiago.La Serena is 3 miles (5 km) away from La Serena city centre and Santiago is 4 miles (8 km) from Santiago city centre.
The cheapest month for a flight from La Serena to Santiago is June.
It's helpful to compare your options as there are 2 ways to travel between La Serena and Santiago including taking a bus and flight.
Since neither La Serena nor Santiago are in the Schengen Area, passport requirements depend on the specific immigration rules of Chile and Chile. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is no time difference between La Serena and Santiago.
The best events to attend in Santiago include:
- Fiesta de la Vendimia, a vibrant wine harvest festival celebrating Chile's winemaking heritage with tastings, music, and cultural events
- Santiago a Mil, an international theater festival featuring performances from around the world in various venues across the city
- Fiestas Patrias, Chile's national celebrations with parades, traditional food, and folk music honoring the country's independence.
The best holidays to experience in Santiago include:
- Fiestas Patrias, vibrant national celebrations with parades, traditional music, and delicious food
- New Year’s Day, lively festivities and fireworks to welcome the new year in a warm climate
- Easter, a time for cultural and religious observances with beautiful processions.
The best season to visit Santiago is Spring or Fall. The best weather to explore Santiago is during September-November or March-May.
We recommend using the bus as it is the most popular way to get from La Serena to Santiago among Omio's users.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
Chile uses the Chilean Peso (CLP) as its currency. Travelers generally find it convenient to use cards in urban areas and larger establishments, but cash is recommended for smaller shops, markets, and rural locations where card acceptance may be limited.
In Santiago, travelers should be cautious of pickpocketing and bag snatching, especially in crowded areas like public transport, markets, and tourist spots. Common scams include overcharging by taxi drivers who do not use meters and counterfeit currency. It's advisable to use authorized taxis or ride-hailing apps and remain vigilant with personal belongings to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular airports
Popular airports from La Serena to Santiago
Most La Serena to Santiago flights use the La Serena to Santiago airport pair. Use this guide to compare La Serena and Santiago airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Departure airports in La Serena
Arrival airports in Santiago
Which La Serena airport do flights to Santiago leave from?
Flights from La Serena to Santiago depart from La Serena. The airport is 3 miles (5 km) from La Serena city centre at La Florida Airport, Coquimbo, La Serena, Coquimbo, Chile.
La Serena (LSC)La Florida Airport, Coquimbo, La Serena, Coquimbo, Chile
City-centre transport
Getting to La Serena from La Serena city centre
La Serena is 5 km from La Serena city centre. Public transport options include:
TRUE
La Serena airport facilities and services
La Serena has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several food outlets available in the terminal.
Wi-Fi and ATMs
Free Wi-Fi available throughout the terminal. ATMs are aTMs available near the entrance.
Tickets and information
Ticket office support is available at La Serena.
Parking, taxis and toilets
Available at La Serena: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at La Serena: The airport is fully accessible with ramps and elevators.
Which Santiago airport do flights from La Serena arrive at?
Flights from La Serena to Santiago arrive at Santiago. Santiago is 4 miles (8 km) from Santiago city centre.
Santiago (SCL)Avenida Américo Vespucio 901, Pudahuel, Santiago, Chile
City-centre transport
Getting to Santiago from Santiago city centre
Santiago is 8 km from Santiago city centre. Public transport options include:
Bus Centropuerto, Pajaritos Station, 19 km
Santiago airport facilities and services
Santiago has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food and drink
Food options include: Restaurants available in both domestic and intertiol terminals; options include fast food and Chilean cuisine.
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are located in both domestic and intertiol terminals.
Luggage and lost property
Lost and found is available at the station.
Parking, taxis and toilets
Available at Santiago: Parking, Taxis, WC.
Bike and car services
Available at Santiago: Car Rental.
Accessibility
Accessibility facilities are available at Santiago: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Hotels nearby include Holiday Inn Santiago Airport, within walking distance..
More options for your journey from La Serena to Santiago
Here are some other resources that might have the information you need
Most popular flights to and from Santiago and La Serena
Most popular flights to Santiago
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