- Must visit
Tampa Museum of Art
Modern and classical art museum on the Riverwalk, known for its contemporary exhibitions and prominent downtown setting.
Flights from Knoxville, TN to Tampa, FL depart on average 2 times per day, taking around 1h 42m. Cheap flight tickets for this journey start at $140 (€113) if you book in advance.
There are 2 flights per day. The earliest flight runs at 07:00, the last at 21:55. The fastest flight covers the 560 miles (902 km) distance in 1h 43m. September is the cheapest month to fly.
Distance 560 miles (902 km) |
Average flight duration 1h 42m |
Cheapest ticket price $140 (€113) |
Flights per day 2 |
Direct flights 2 |
Fastest flight 1h 43m |
First flight 7:00 AM |
Last flight 9:55 PM |
Cheapest Month Sep |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Apr - Jun |
Omio recommends booking the flight as it is the most popular option from Knoxville, TN to Tampa, FL among Omio's users. If you are prioritising price take the flight with prices starting from $140. For those with little time consider booking a flight which can get you there in 1h 42m. The ticket price range depends on the travel mode: a flight costs an average of $140, and a bus costs an average of $157.
Distance: 560 miles (902 km)
Most popular Flight | Bus | Driving |
|---|---|---|
$140 Average price Cheapest | $181 Average price | $15 Average price (fuel + tolls) |
4h 42m Average total duration Fastest 1h 42m Onboard + 3h 0m Additional time* | 17h 5m Average total duration 16h 35m Onboard + 30m Additional time* | 9h 44m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Knoxville, TN to Tampa, FL:
A flight is $40 (€32) less than a bus for this route with tickets for a bus from Knoxville, TN to Tampa, FL costing on average $181 (€146).
Other travel options to Tampa, FL take longer:
Bus takes on average 16h 35m.
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Tampa — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Tampa trip today.
Modern and classical art museum on the Riverwalk, known for its contemporary exhibitions and prominent downtown setting.
World-famous Salvador Dalí museum across the bay in St. Petersburg, frequently visited from Tampa for its iconic collection and architecture.
Historic museum inside the former Tampa Bay Hotel, showcasing Gilded Age architecture and Tampa history.
Signature waterfront promenade linking museums, parks, and public art, and one of the city's most popular walking areas.
Historic neighborhood famous for brick streets, cigar heritage, nightlife, and distinctive cultural character.
Scenic waterfront boulevard popular for walking, running, and skyline views along Hillsborough Bay.
Tampa’s signature sandwich, traditionally layered with Cuban bread, roast pork, ham, salami, Swiss cheese, pickles, and mustard, then pressed hot. The salami reflects the city’s Italian influence in Y
A classic Ybor City snack made with spiced crab meat mixed with breadcrumbs, formed into a shell-like shape, breaded, and fried. It reflects Tampa’s cigar-factory immigrant history and is one of the c
A Florida Gulf Coast favorite often found in Tampa, featuring fresh local grouper grilled, blackened, or fried on a bun. It is especially popular for showcasing the region’s seafood.
Iconic fine-dining destination famous for dry-aged steaks, an extensive wine collection, and classic Tampa special-occasion dining.
Historic Ybor City institution known for Spanish-Cuban cuisine, the 1905 Salad, and flamenco performances in a grand old-world setting.
Popular riverfront restaurant serving Florida-inspired dishes, charbroiled oysters, and native-inspired flavors in a lively upscale-casual atmosphere.
Moderate for U.S. travelers. Dining and transport are manageable, while hotels rise in peak season and waterfront areas.
Tip 18-20% at restaurants. USD 1-2 per drink at bars, round up taxis, and tip hotel staff USD 2-5. Tips are expected for table service.
Find answers to the most common questions about traveling from Knoxville, TN to Tampa, FL by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Tampa, FL, this guide helps you travel smarter and with confidence.

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