- Recommended
East Tennessee History Center
Engaging museum on regional history with permanent and rotating exhibits covering people, places, and events from East Tennessee's past.
Take a flight from Gainesville, FL to Knoxville, TN and enjoy the approximately 445 miles (717 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest flight runs at 11:33, the last at 11:33.
Distance 445 miles (717 km) |
First flight 11:33 AM |
Last flight 11:33 AM |
High Season Jul - Sep |
Low Season Jan - Mar |
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Knoxville, TN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Knoxville, TN trip today.
Engaging museum on regional history with permanent and rotating exhibits covering people, places, and events from East Tennessee's past.
University museum featuring changing exhibitions of American and international art in a modern gallery setting near campus.
Historic house museum preserving the home of artist Adelia Armstrong Lutz, with decorative arts, local history, and period rooms.
Lively pedestrian-friendly square lined with shops, events, and public seating. It is a central gathering place and a great base for exploring downtown.
Urban park from the 1982 World's Fair with lawns, walking paths, performance spaces, and easy access to the Sunsphere and museums.
Historic warehouse district with brick streets, galleries, murals, and nightlife. It blends railroad-era character with a creative local feel.
Smoky pulled pork barbecue is a regional staple in East Tennessee, usually hickory-smoked and served with slaw and sauce at local cookouts and barbecue joints.
Fried catfish is a longtime Tennessee favorite, coated in cornmeal and served with hush puppies or sides, especially popular in casual Southern eateries.
Biscuits with sausage gravy are a classic Southern breakfast in Knoxville, featuring flaky biscuits topped with rich peppery gravy made with pork drippings and milk.
Long-running neighborhood restaurant known for hearty Southern comfort food, pies, and a warm, traditional dining room.
Upscale Southern restaurant in Market Square known for shrimp and grits, steaks, and a polished downtown atmosphere.
Casual old-school barbecue spot serving hickory-smoked pork, ribs, and classic East Tennessee sides in a relaxed setting.
Moderate for U.S. city breaks: hotels and dining are reasonable, while car travel is common and public transit is limited for tourists.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-2 per drink or coffee is appreciated at cafes.
Find answers to the most common questions about traveling from Gainesville, FL to Knoxville, TN by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.

Most Gainesville, FL to Knoxville, TN flights use the Gainesville Regional Airport to Knoxville airport pair. Use this guide to compare Gainesville, FL and Knoxville, TN airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Gainesville Regional Airport is 6 km from Gainesville city centre. Public transport options include:
Gainesville Regional Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: One cafe available
Free Wi-Fi throughout the terminal. ATMs are located near the entrance.
Ticket office support is available at Gainesville Regional Airport.
Available at Gainesville Regional Airport: Parking, Taxis, WC.
Accessibility facilities are available at Gainesville Regional Airport: Wheelchair accessible with assistance available.
Knoxville is 2 km from Knoxville city centre. Public transport options include:
Knoxville has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants in Concourse A and B, including Ruby Tuesday and Quiznos
Free Wi-Fi available throughout the airport. ATMs are located near ticketing and baggage claim.
Lost and found is available at the station.
Available at Knoxville: Parking, Taxis, WC.
Available at Knoxville: Car Rental.
Accessibility facilities are available at Knoxville.
Nearby hotels include Hotels within walking distance, including Hilton Knoxville Airport..
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