- Must visit
Columbia Museum of Art
Major art museum with American, European, and Asian works plus rotating exhibitions in a central downtown setting.
Omio recommends booking the flight as it is the most popular option from Wilmington, NC to Columbia, SC among Omio's users. If you are prioritising price, take the flight, with an average ticket price of €570 For those with little time, consider booking a flight, which has an average total journey time of 4h 43m. Average ticket prices depend on the travel mode: a flight costs an average of €570, while a flight costs an average of €570.
Distance: 177 miles (286 km)
Most popular Flight | Driving |
|---|---|
€570 Average price Cheapest | €33 Average price (fuel + tolls) |
4h 43m Average total duration Fastest 2h 43m Onboard + 2h 0m Additional time* | 3h 9m Average total duration (door-to-door) |
![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options |
Compare train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a bus from Wilmington, NC to Columbia, SC and enjoy the approximately 177 miles (286 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 04:13, the last at 09:15.
Distance 177 miles (286 km) |
First bus 4:13 AM |
Last bus 9:15 AM |
High Season Jul - Sep |
Low Season Oct - Dec |
Discover the best of Columbia, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Columbia, SC trip today.
Major art museum with American, European, and Asian works plus rotating exhibitions in a central downtown setting.
State museum covering art, history, science, and technology with immersive galleries and family-friendly exhibits.
Military history museum with artifacts, uniforms, and exhibits on South Carolina service members across multiple conflicts.
Popular riverside green space with trails, historic canal views, and shaded walks near downtown and the river confluence.
Revived warehouse district with galleries, public art, shops, and event spaces that showcase Columbia's creative scene.
Lively university district with boutiques, murals, nightlife, and walkable blocks popular with locals and students.
Find answers to the most common questions about traveling from Wilmington, NC to Columbia, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Columbia, SC, this guide helps you travel smarter and with confidence.

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