- Must visit
Museo Regional de Iquique
Preserved saltpeter-era workers' office and home displays in a wooden historic building. A concise introduction to regional social history.
The best way to find a cheap bus ticket from Santiago to Iquique is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santiago to Iquique will cost around $65 if you buy it on the day, but the cheapest tickets can be found for only $53.
On Mon, Nov 02, we found 5 buses from Santiago to Iquique, including 5 direct services.
On Mon, Nov 02 the direct buses cover the 1473 km distance in an average of 1 d 27 m but if you time it right, some buses will get you there in just 1 d 5 m .
On Mon, Nov 02 the slowest buses will take 1 d 1 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Santiago to Iquique run on average 4 times per day, taking around 23h 50m. Cheap bus tickets for this journey start at $37 but you can travel from only $36 by flight.
There are 2 buses per day. The earliest bus runs at 06:50, the last at 21:15. The fastest bus covers the 915 miles (1473 km) distance in 23h 30m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Santiago to Iquique.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:50AM | Arrival Time 07:55AM | Duration 25h05 | Departure days Fri, Sat | Cheapest price $46 |
Operator FlixBus | Departure Time 07:50AM | Arrival Time 07:55AM | Duration 24h05 | Departure days Tue, Fri, Sat, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 10:05AM | Arrival Time 11:05AM | Duration 25h00 | Departure days Fri | Cheapest price $46 |
Operator FlixBus | Departure Time 10:35AM | Arrival Time 11:05AM | Duration 24h30 | Departure days Tue, Sat, Sun | Cheapest price $46 |
Operator FlixBus | Departure Time 10:50AM | Arrival Time 10:55AM | Duration 24h05 | Departure days Mon, Wed, Thu | Cheapest price $71 |
Operator FlixBus | Departure Time 11:00AM | Arrival Time 11:05AM | Duration 24h05 | Departure days Tue, Fri, Sat, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 11:50AM | Arrival Time 11:55AM | Duration 24h05 | Departure days Wed, Thu | Cheapest price $39 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 02:05PM | Duration 25h00 | Departure days Mon | Cheapest price $62 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 02:05PM | Duration 24h05 | Departure days Mon, Wed | Cheapest price $56 |
Operator FlixBus | Departure Time 02:05PM | Arrival Time 03:05PM | Duration 25h00 | Departure days Mon | Cheapest price $61 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 03:05PM | Duration 24h05 | Departure days Mon, Wed | Cheapest price $48 |
The table below shows live departures for Santiago to Iquique buses for today, Sunday, November 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 7:50 AM Santiago, Terminal de Buses San Borja | 24h05 | 7:55 AM Iquique, Terminal Rodoviario | 0 transfersDirect | |
FlixBus · FlixBus | 10:35 AM Santiago, Los Libertadores | 24h30 | 11:05 AM Iquique, Terminal Rodoviario | 1 transfer | |
FlixBus | 11:00 AM Santiago, Terminal de Buses San Borja | 24h05 | 11:05 AM Iquique, Terminal Rodoviario | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Santiago to Iquique with FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Iquique — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Iquique trip today.
Preserved saltpeter-era workers' office and home displays in a wooden historic building. A concise introduction to regional social history.
Museum dedicated to the corvette Esmeralda and the 1879 naval battle. Good for understanding one of Chile's defining historic events.
Naval museum covering the War of the Pacific, maritime heritage, and local seafaring history through documents, models, and artifacts.
Main civic square framed by palms, the clock tower, and historic buildings. A classic meeting point and base for walking the old center.
Historic pedestrian street lined with preserved wooden facades and shops. Ideal for architecture, photos, and a short heritage walk.
Urban beach area with broad sand, surf culture, and a long seafront walk. A lively place to relax or watch sports and sunsets.
Northern Chilean ceviche of fresh fish cured in lime with onion and cilantro. A coastal staple in Iquique thanks to the city’s strong fishing tradition.
Seafood soup made with local shellfish or fish, onion, garlic, and broth. It is a classic restorative dish along Chile’s northern coast.
Hearty fish or seafood stew usually cooked with potato, tomato, pepper, and stock. Popular in port cities as a homestyle coastal meal.
Established seafood restaurant known for fresh fish, ceviche, and classic Chilean coastal dishes in a relaxed setting near central Iquique.
Well-known local spot for Peruvian and Chilean seafood, especially ceviche and arroz con mariscos, with a casual atmosphere.
Refined dining room focused on seafood and grilled dishes, suited to a more polished meal with ocean views in Iquique.
Moderate for Chilean beach cities: hotels can rise in peak season, dining is reasonable, and local buses are cheap for tourists.
Restaurants often add a 10% service tip, commonly accepted. Round up in cafes. Taxis do not require tips, but rounding up the fare is polite.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Iquique.
Find answers to the most common questions about traveling from Santiago to Iquique by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Iquique, this guide helps you travel smarter and with confidence.

Most Santiago to Iquique buses use the Santiago, Terminal de Buses San Borja to station pair. Use this guide to compare Santiago and Iquique bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Santiago, Terminal de Buses San Borja is 2 km from Santiago city centre. Public transport options include:
Santiago, Terminal de Buses San Borja has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast food and traditional eateries are available.
Free Wi-Fi available inside terminal. ATMs are several ATMs located within the terminal.
Ticket office support is available at Santiago, Terminal de Buses San Borja.
Available at Santiago, Terminal de Buses San Borja: Parking, Taxis, WC.
Accessibility facilities are available at Santiago, Terminal de Buses San Borja: Wheelchair accessible entrances and exits available.
Santiago, Los Libertadores is 10 km from Santiago city centre. Public transport options include:
Santiago, Los Libertadores has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast food outlets and cafes are available.
Free Wi-Fi is available throughout the station. ATMs are aTMs are located near the ticket office.
Ticket office support is available at Santiago, Los Libertadores.
Available at Santiago, Los Libertadores: Parking, Taxis, WC.
Accessibility facilities are available at Santiago, Los Libertadores: The station is wheelchair accessible.