- Must visit
Denver Art Museum
Major art museum known for Indigenous arts, Western American collections, and striking modern architecture. One of Denver’s signature cultural attractions.
Omio recommends booking the flight as it is the most popular option from Odessa, TX to Denver, CO among Omio's users. If you are prioritising price take the bus with prices starting from $179. For those with little time consider booking a flight which can get you there in 3h 37m. The ticket price range depends on the travel mode: a bus costs an average of $179, and a flight costs an average of $359.
Distance: 564 miles (909 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$255 Average price Cheapest | $448 Average price | $137 Average price (fuel + tolls) |
26h 59m Average total duration 26h 29m Onboard + 30m Additional time* | 6h 37m Average total duration Fastest 3h 37m Onboard + 3h 0m Additional time* | 10h 4m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Odessa, TX to Denver, CO:
A bus is $193 (€155) less than a flight for this route with tickets for a flight from Odessa, TX to Denver, CO costing on average $448 (€361).
Other travel options to Denver, CO take longer:
Bus takes on average 26h 29m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 11:55AM | Arrival Time 02:55PM | Duration 27h00 | Departure days Tue, Thu | Cheapest price $263 |
Operator Greyhound | Departure Time 12:55PM | Arrival Time 01:50PM | Duration 24h55 | Departure days Thu, Sun | Cheapest price $179 |
Compare flight and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Odessa, TX to Denver, CO run on average 1 times per day, taking around 26h 29m. Cheap bus tickets for this journey start at $179 (€144) if you book in advance.
The earliest bus runs at 06:55, the last at 20:10. The fastest bus covers the 564 miles (909 km) distance in 24h 55m.
Distance 564 miles (909 km) |
Average bus duration 26h 29m |
Cheapest ticket price $179 (€144) |
Buses per day 1 |
Fastest bus 24h 55m |
First bus 6:55 AM |
Last bus 8:10 PM |
Cheapest Month Oct |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jul - Sep |
Discover the best of Denver — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Denver trip today.
Major art museum known for Indigenous arts, Western American collections, and striking modern architecture. One of Denver’s signature cultural attractions.
Large science and natural history museum with dinosaurs, space, wildlife, and family-friendly exhibitions. A top choice for broad appeal.
Contemporary art museum featuring rotating exhibitions, experimental works, and a rooftop with city views. Popular with younger visitors and local art fans.
Dramatic red rock landscape, concert venue, hiking area, and one of the region’s most famous scenic destinations.
Creative neighborhood known for murals, galleries, warehouses, and social-media-friendly street art. One of Denver’s trendiest areas.
Lower Downtown combines historic warehouses, nightlife, and easy access to Union Station. A key area for first-time visitors.
Denver’s signature spicy stew or sauce made with roasted green chiles, often served over burritos, fries, eggs, or burgers. It reflects the city’s strong Colorado and Southwestern food culture.
A large flour tortilla filled with eggs, potatoes, cheese, and often bacon or sausage, then covered in green chile. It is a classic Denver breakfast found in diners across the city.
A Colorado frontier specialty made from breaded and fried bull testicles, usually served with dipping sauce. It is one of the region’s most famous novelty dishes.
Respected Larimer Square restaurant offering refined Mediterranean-influenced cuisine in an elegant but approachable setting. A reliable choice for a higher-end Denver dinner.
Established adobe-style restaurant near Denver known for Colorado frontier cuisine, including bison, elk, and other regional specialties in a distinctive Southwestern setting.
Well-known LoHi restaurant with creative New American dishes, strong brunch service, and a stylish atmosphere. Popular for locally sourced ingredients and vegetarian-friendly options.
Moderate by major U.S. city standards. Hotels can be pricey in peak season, but casual dining and transit are manageable.
Tip 18-20% at restaurants; 20%+ for great service. Bars: USD 1-2 per drink. Taxis/rideshares: 10-15%. Hotels: USD 2-5 for housekeeping; USD 1-2 per bag.
Find answers to the most common questions about traveling from Odessa, TX to Denver, CO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Denver, CO, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need