- Must visit
Vatican Museums
A vast complex of papal collections with masterpieces from antiquity to the Renaissance. A global essential for art, history, and iconic galleries.
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Travel Information
Compare train, bus, and flight for Mestre to Vatican
Omio recommends booking the bus as it is the most popular option from Mestre to Vatican among Omio's users. If you are prioritising price take the bus with prices starting from $18. For those with little time consider booking a flight which can get you there in 1h 12m. The ticket price range depends on the travel mode: a bus costs an average of $18, and a flight costs an average of $103.
Distance: 247 miles (399 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$35 Average price Cheapest | $60 Average price | $152 Average price | $106 Average price (fuel + tolls) |
9h 16m Average total duration 8h 46m Onboard + 30m Additional time* | 9h 45m Average total duration 9h 15m Onboard + 30m Additional time* | 4h 12m Average total duration Fastest 1h 12m Onboard + 3h 0m Additional time* | 5h 9m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Mestre to Vatican is a bus with an average price of $35.
This is compared to other travel options from Mestre to Vatican:
A bus is $25 less than a train for this route with tickets for a train from Mestre to Vatican costing on average $60.
A bus is $117 less than a flight for this route with tickets for a flight from Mestre to Vatican costing on average $152.
The fastest way to travel from Mestre to Vatican is by flight with an average journey time of 1h 12m.
Other travel options to Vatican take longer:
Bus takes on average 8h 46m.
Train takes on average 9h 15m.
It's helpful to compare your options as there are 3 ways to travel between Mestre and Vatican including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Mestre to Vatican among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Mestre to Vatican Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:50AM | Arrival Time 09:15AM | Duration 8h25 | Departure days Tue, Sat | Cheapest price $72 |
Operator FlixBus | Departure Time 06:30AM | Arrival Time 01:53PM | Duration 7h23 | Departure days Sat | Cheapest price $72 |
Operator FlixBus | Departure Time 06:40AM | Arrival Time 02:39PM | Duration 7h59 | Departure days Sat | Cheapest price $72 |
Operator FlixBus | Departure Time 10:10AM | Arrival Time 06:25PM | Duration 8h15 | Departure days Fri | Cheapest price $39 |
Operator FlixBus | Departure Time 10:45AM | Arrival Time 06:06PM | Duration 7h21 | Departure days Sat | Cheapest price $72 |
Operator FlixBus | Departure Time 11:10AM | Arrival Time 07:25PM | Duration 8h15 | Departure days Mon, Thu | Cheapest price $22 |
Operator FlixBus | Departure Time 12:10PM | Arrival Time 08:52PM | Duration 8h42 | Departure days Sat | Cheapest price $76 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 10:15PM | Duration 9h10 | Departure days Sat | Cheapest price $72 |
Operator FlixBus | Departure Time 02:20PM | Arrival Time 10:03PM | Duration 7h43 | Departure days Sat | Cheapest price $72 |
Operator FlixBus | Departure Time 02:55PM | Arrival Time 03:00AM | Duration 12h05 | Departure days Mon | Cheapest price $18 |
Operator Marino Autolinee | Departure Time 08:30PM | Arrival Time 03:30AM | Duration 7h00 | Departure days Sun | Cheapest price $67 |
Operator FlixBus | Departure Time 08:35PM | Arrival Time 05:54AM | Duration 9h19 | Departure days Sat | Cheapest price $72 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 06:50AM | Duration 9h40 | Departure days Sat | Cheapest price $72 |
Compare prices and tickets Mestre to Vatican by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Mestre to Vatican buses with Omio?
FlixBus operates all buses services from Mestre to Vatican.
Omio is an official ticket reseller for all your travel options from Mestre to Vatican.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Mestre to Vatican.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Mestre to Vatican.
Journey information
Overview: Bus from Mestre to Vatican
Italy
Vatican City State
Buses from Mestre to Vatican run on average 16 times per day, taking around 8h 46m. Cheap bus tickets for this journey start at $18 if you book in advance.
There are 6 buses per day. The earliest bus runs at 00:50, the last at 23:05. The fastest bus covers the 247 miles (399 km) distance in 7h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 247 miles (399 km) |
Average bus duration 8h 46m |
Cheapest ticket price $18 |
Buses per day 16 |
Direct buses 6 |
Fastest bus 7h 0m |
First bus 12:50 AM |
Last bus 11:05 PM |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Apr - Jun |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 63 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus from Mestre to VaticanYou can travel by bus between Mestre to Vatican with FlixBus for as low as $18. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
8h 15m
Cheapest Price
$18
FlixBus frequency
8 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Vatican
Things to do in Vatican
Discover the best of Vatican — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Vatican trip today.
- Must visit
Raphael Rooms
Home to Raphael’s fresco cycles, including The School of Athens. These rooms are among the Vatican’s greatest artistic highlights and a major museum draw.
- Must visit
Gallery of Maps
This gallery presents maps of Italy in a long frescoed corridor. It is both visually striking and historically fascinating within the museum route.
- Must visit
St. Peter's Square
This broad ceremonial piazza is Vatican City’s main gathering place, offering classic basilica views, fountains, and a powerful sense of scale.
- Must visit
Bernini's Colonnades
Bernini’s embracing colonnades create one of the world’s great urban spaces. Walk here for architecture, symmetry, and changing light across the square.
- Must visit
St. Peter's Dome
The basilica dome terraces deliver one of Rome’s most famous viewpoints, with close-up architecture and sweeping city vistas.
- Vegetarian
Cacio E Pepe
Cacio e Pepe is a Roman pasta with Pecorino Romano and black pepper. It is a local staple around Vatican City for its simplicity and strong regional identity.
Pasta Alla Carbonara
Carbonara is pasta with egg, Pecorino Romano, guanciale, and pepper. It is one of Rome's most famous dishes and widely served in trattorias near the Vatican.
Pasta All'Amatriciana
Amatriciana is pasta with tomato, guanciale, and Pecorino Romano. Though linked to Amatrice, it is a classic Roman favorite commonly eaten near the Vatican.
Il Sorpasso
Traditional Roman trattoria in Prati known for pasta classics and a lively local atmosphere, convenient for Vatican visitors.
Da Vito e Dina
Long-established Roman restaurant near the Vatican serving cacio e pepe, amatriciana, and other regional staples in a classic setting.
La Zanzara
Refined dining room in Prati with polished Roman and Italian dishes, strong wine list, and a more upscale atmosphere.
Euro (€)
Very high tourist demand and limited lodging nearby make stays pricey. Dining is similar to central Rome, while transit costs are low if using Rome buses and metro.
Average meal costs
- Budget
- €8-15 for fast food or casual takeaway.
- Mid-range
- €20-40 per person for a restaurant meal.
- Fine dining
- €60+ per person for upscale restaurants.
- Coffee
- €1.50-3.50 for espresso or cappuccino.
Tipping culture
Service may be included. Round up or leave 5-10% at restaurants for good service. Taxis are usually rounded up. Small change is fine at cafés.
TicketAppy
Get the appOfficial public transport app
Prices
- Single ticket
- €1.50
- Day pass
- €7.00
To the city center
Vatican City Railway Station -> Piazza Venezia
- Distance
- 3 km
- Travel time
- 15 min
- Vatican City has no separate urban transit system; use Rome ATAC buses, metro and trams with standard BIT tickets. A single ticket is valid for 100 min.
- Contactless bank card payment is available on many ATAC buses, trams and metro gates via Tap & Go, but carry a backup ticket as not every vehicle is equipped.
FAQs: Bus from Mestre to Vatican
Find answers to the most common questions about traveling from Mestre to Vatican by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Vatican, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Mestre to Vatican can start from as little as $18 when you book in advance. The average bus ticket price for Mestre to Vatican is $35 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Mestre to Vatican is 7h 0m to travel the 247 miles (399 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Mestre to Vatican leaves at 12:50 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Mestre to Vatican leaves at 11:05 PM.
Yes, there are 6 direct buses a day from Mestre to Vatican with . Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Mestre to Vatican, you can count on FlixBus for the best way to get you to Vatican. You can also check all possible bus companies who offer a service between Mestre and Vatican and compare the amenities they offer before buying a bus ticket.
A trip to Vatican from Mestre is worth doing but not as a day trip with a journey time of 7h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Mestre to Vatican is February.
It's helpful to compare your options as there are 3 ways to travel between Mestre and Vatican including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Mestre to Vatican:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Mestre to Vatican for bus company FlixBus.
Whether you can cancel your bus ticket from Mestre to Vatican depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Mestre to Vatican.
Yes, the following luggage options are included when booking a bus ticket from Mestre to Vatican:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Mestre to Vatican:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Mestre to Vatican. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Mestre to Vatican with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Mestre to Vatican with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Mestre to Vatican with the following bus company: FlixBus.
Since both Mestre and Vatican are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the bus as it is the most popular way to get from Mestre to Vatican among Omio's users.
Vatican City uses the euro (€) as its official currency. Travelers find it convenient to use both cash and cards, but cash is often preferred for small purchases and in places where card acceptance may be limited.
In the Vatican, travelers should be cautious of pickpocketing, especially in crowded areas like St. Peter’s Square and the Vatican Museums. Scams involving unofficial ticket sellers offering overpriced or fake entry passes are common, so purchasing tickets from official sources is recommended. Additionally, travelers should be aware of aggressive vendors selling souvenirs outside key sites. Security checks are strict, so following all regulations and respecting dress codes is important to avoid issues.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
Most popular bus connections from Mestre
More options for your journey from Mestre to Vatican
Here are some other resources that might have the information you need
Most popular buses to and from Vatican and Mestre
Most popular bus connections to Vatican
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