- Must visit
Vatican Museums
A vast complex of papal collections with masterpieces from antiquity to the Renaissance. A global essential for art, history, and iconic galleries.
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The cheapest and fastest buses from Mestre to Vatican
Showing times, prices and bookable tickets for Sep 19
Cheapest price on Sep 19
$55
Average ticket price on Sep 19
$55
Fastest journey on Sep 19
7 h
Average journey duration on Sep 19
7 h
Buses on Sep 19
1
Distance
399 km
Cheap tickets
The best way to find a cheap bus ticket from Mestre to Vatican is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mestre to Vatican will cost around $55 if you buy it on the day, but the cheapest tickets can be found for only $55.
Fast buses
It's difficult to get from Mestre to Vatican without transferring at least once.
065 · 0559:30 PM7h00Venezia, Viale Stazione (Mestre Stazione - fermata ATVO)4:30 AMRoma, Autostazione Tiburtina$551One-way1 transfer
- 065 · 0559:30 PM7h00Venezia, Viale Stazione (Mestre Stazione - fermata ATVO)4:30 AMRoma, Autostazione Tiburtina$551One-way1 transfer
Travel Information
Compare train and bus for Mestre to Vatican
Omio recommends booking the train as it is the most popular option from Mestre to Vatican among Omio's users.
Distance: 247 miles (399 km)
Compare bus with
| Bus | Most popular Train | Driving |
|---|---|---|
$107 Average price (fuel + tolls) | ||
5h 9m Average total duration (door-to-door) | ||
Direct Options | Direct Options | Direct Options |
Mestre to Vatican Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 10:10AM | Arrival Time 06:25PM | Duration 8h15 | Departure days Fri | Cheapest price $38 |
Operator FlixBus | Departure Time 11:10AM | Arrival Time 07:25PM | Duration 8h15 | Departure days Mon, Thu | Cheapest price $22 |
Operator FlixBus | Departure Time 02:55PM | Arrival Time 03:00AM | Duration 12h05 | Departure days Mon | Cheapest price $18 |
Operator Marino Autolinee | Departure Time 08:30PM | Arrival Time 03:30AM | Duration 7h00 | Departure days Sun | Cheapest price $67 |
Operator Marino Autolinee | Departure Time 09:30PM | Arrival Time 04:30AM | Duration 7h00 | Departure days Tue, Sat | Cheapest price $55 |
Compare prices and tickets Mestre to Vatican by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Sep 19
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Why should you book Mestre to Vatican buses with Omio?
FlixBus operates all buses services from Mestre to Vatican.
Omio is an official ticket reseller for all your travel options from Mestre to Vatican.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Mestre to Vatican.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Mestre to Vatican.
Journey information
Overview: Bus from Mestre to Vatican
Italy
Vatican City State
Take a bus from Mestre to Vatican and enjoy the approximately 247 miles (399 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 00:50, the last at 23:05.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 247 miles (399 km) |
First bus 12:50 AM |
Last bus 11:05 PM |
Cheapest Month Feb |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 28 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Complete guide to Vatican
Things to do in Vatican
Discover the best of Vatican — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Vatican trip today.
- Must visit
Raphael Rooms
Home to Raphael’s fresco cycles, including The School of Athens. These rooms are among the Vatican’s greatest artistic highlights and a major museum draw.
- Must visit
Gallery of Maps
This gallery presents maps of Italy in a long frescoed corridor. It is both visually striking and historically fascinating within the museum route.
- Must visit
St. Peter's Square
This broad ceremonial piazza is Vatican City’s main gathering place, offering classic basilica views, fountains, and a powerful sense of scale.
- Must visit
Bernini's Colonnades
Bernini’s embracing colonnades create one of the world’s great urban spaces. Walk here for architecture, symmetry, and changing light across the square.
- Must visit
St. Peter's Dome
The basilica dome terraces deliver one of Rome’s most famous viewpoints, with close-up architecture and sweeping city vistas.
- Vegetarian
Cacio E Pepe
Cacio e Pepe is a Roman pasta with Pecorino Romano and black pepper. It is a local staple around Vatican City for its simplicity and strong regional identity.
Pasta Alla Carbonara
Carbonara is pasta with egg, Pecorino Romano, guanciale, and pepper. It is one of Rome's most famous dishes and widely served in trattorias near the Vatican.
Pasta All'Amatriciana
Amatriciana is pasta with tomato, guanciale, and Pecorino Romano. Though linked to Amatrice, it is a classic Roman favorite commonly eaten near the Vatican.
Il Sorpasso
Traditional Roman trattoria in Prati known for pasta classics and a lively local atmosphere, convenient for Vatican visitors.
Da Vito e Dina
Long-established Roman restaurant near the Vatican serving cacio e pepe, amatriciana, and other regional staples in a classic setting.
La Zanzara
Refined dining room in Prati with polished Roman and Italian dishes, strong wine list, and a more upscale atmosphere.
Euro (€)
Very high tourist demand and limited lodging nearby make stays pricey. Dining is similar to central Rome, while transit costs are low if using Rome buses and metro.
Average meal costs
- Budget
- €8-15 for fast food or casual takeaway.
- Mid-range
- €20-40 per person for a restaurant meal.
- Fine dining
- €60+ per person for upscale restaurants.
- Coffee
- €1.50-3.50 for espresso or cappuccino.
Tipping culture
Service may be included. Round up or leave 5-10% at restaurants for good service. Taxis are usually rounded up. Small change is fine at cafés.
TicketAppy
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Prices
- Single ticket
- €1.50
- Day pass
- €7.00
To the city center
Vatican City Railway Station -> Piazza Venezia
- Distance
- 3 km
- Travel time
- 15 min
- Vatican City has no separate urban transit system; use Rome ATAC buses, metro and trams with standard BIT tickets. A single ticket is valid for 100 min.
- Contactless bank card payment is available on many ATAC buses, trams and metro gates via Tap & Go, but carry a backup ticket as not every vehicle is equipped.
FAQs: Bus from Mestre to Vatican
Find answers to the most common questions about traveling from Mestre to Vatican by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Vatican, this guide helps you travel smarter and with confidence.
Most popular bus connections from Mestre
More options for your journey from Mestre to Vatican
Here are some other resources that might have the information you need
Most popular buses to and from Vatican and Mestre
Most popular bus connections to Vatican
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