- Must visit
Museo Castromediano
Major museum of Apulian archaeology with Messapian, Roman, and medieval finds. Essential for understanding Lecce and Salento before exploring the city.
Cheapest price on Oct 07
€3
Average ticket price on Oct 07
€4
Fastest journey on Oct 07
1 h 10 m
Average journey duration on Oct 07
2 h 3 m
Buses on Oct 07
3
Distance
38 km
The best way to find a cheap bus ticket from Mesagne to Lecce is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mesagne to Lecce will cost around €4 if you buy it on the day, but the cheapest tickets can be found for only €3.
On Wed, Oct 07, we found 3 buses from Mesagne to Lecce, including 3 direct services.
On Wed, Oct 07 the direct buses cover the 38 km distance in an average of 2 h 3 m but if you time it right, some buses will get you there in just 1 h 10 m .
On Wed, Oct 07 the slowest buses will take 3 h 48 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Take a bus from Mesagne to Lecce and enjoy the approximately 23 miles (38 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 04:21, the last at 23:00.
Distance 23 miles (38 km) |
First bus 4:21 AM |
Last bus 11:00 PM |
Cheapest Month Nov |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Fri |
Least Busy Day Tue |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Ferrovie del Sud Est | Departure Time 04:45AM | Arrival Time 06:00AM | Duration 1h15 | Departure days Mon, Wed, Thu, Fri, Sat | Cheapest price €3 |
Operator Ferrovie del Sud Est | Departure Time 05:45AM | Arrival Time 06:55AM | Duration 1h10 | Departure days Mon, Wed, Thu, Fri, Sat | Cheapest price €3 |
Operator Ferrovie del Sud Est | Departure Time 06:45AM | Arrival Time 07:55AM | Duration 1h10 | Departure days Tue | Cheapest price €3 |
Operator | Departure Time 07:01AM | Arrival Time 09:00AM | Duration 1h59 | Departure days Tue | Cheapest price €7 |
Operator Regionale | Departure Time 07:01AM | Arrival Time 10:18AM | Duration 3h17 | Departure days Tue | Cheapest price €9 |
Operator | Departure Time 07:10AM | Arrival Time 09:15AM | Duration 2h05 | Departure days Tue | Cheapest price €5 |
Operator BlaBlaCar | Departure Time 07:15AM | Arrival Time 07:45AM | Duration 0h30 | Departure days Tue | Cheapest price €4 |
Operator BlaBlaCar | Departure Time 07:40AM | Arrival Time 08:30AM | Duration 0h50 | Departure days Tue | Cheapest price €5 |
Operator BlaBlaCar | Departure Time 08:20AM | Arrival Time 08:50AM | Duration 0h30 | Departure days Tue | Cheapest price €3 |
Operator BlaBlaCar | Departure Time 09:40AM | Arrival Time 10:10AM | Duration 0h30 | Departure days Tue | Cheapest price €5 |
Operator | Departure Time 11:45AM | Arrival Time 02:13PM | Duration 2h28 | Departure days Tue | Cheapest price €5 |
Operator Ferrovie del Sud Est | Departure Time 01:50PM | Arrival Time 03:15PM | Duration 1h25 | Departure days Fri | Cheapest price €3 |
Operator Trenitalia | Departure Time 02:05PM | Arrival Time 05:53PM | Duration 3h48 | Departure days Wed, Thu | Cheapest price €6 |
Operator Ferrovie del Sud Est | Departure Time 02:50PM | Arrival Time 04:15PM | Duration 1h25 | Departure days Tue | Cheapest price €3 |
Operator | Departure Time 03:15PM | Arrival Time 06:53PM | Duration 3h38 | Departure days Tue | Cheapest price €6 |
Operator BlaBlaCar | Departure Time 04:00PM | Arrival Time 04:30PM | Duration 0h30 | Departure days Tue | Cheapest price €4 |
Operator | Departure Time 04:30PM | Arrival Time 06:13PM | Duration 1h43 | Departure days Tue | Cheapest price €5 |
Operator Regionale | Departure Time 05:25PM | Arrival Time 07:35PM | Duration 2h10 | Departure days Thu | Cheapest price €9 |
Operator | Departure Time 06:21PM | Arrival Time 08:35PM | Duration 2h14 | Departure days Tue | Cheapest price €9 |
Operator | Departure Time 06:25PM | Arrival Time 08:13PM | Duration 1h48 | Departure days Tue | Cheapest price €5 |
Operator Regionale | Departure Time 06:25PM | Arrival Time 08:35PM | Duration 2h10 | Departure days Tue | Cheapest price €9 |
Operator Frecciarossa | Departure Time 07:55PM | Arrival Time 09:48PM | Duration 1h53 | Departure days Tue | Cheapest price €18 |
Operator | Departure Time 07:55PM | Arrival Time 10:25PM | Duration 2h30 | Departure days Tue | Cheapest price €5 |
Operator | Departure Time 08:28PM | Arrival Time 10:48PM | Duration 2h20 | Departure days Tue | Cheapest price €9 |
Operator Regionale | Departure Time 08:32PM | Arrival Time 10:48PM | Duration 2h16 | Departure days Tue | Cheapest price €9 |
The table below shows live departures for Mesagne to Lecce buses for today, Tuesday, October 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Autobus FS Sud Est 54002 · Autobus FS Sud Est 86020 | 6:45 AM Mesagne | 1h10 | 7:55 AM Lecce, Palazzetto Dello Sport | 1 transfer | |
Autobus FS Sud Est 54002 | 6:45 AM Mesagne | 1h15 | 8:00 AM Lecce, Palazzetto Dello Sport | 0 transfersDirect | |
Regionale 19970+ Autobus FS Sud Est 705B | 7:01 AM Mesagne | 3h17 | 10:18 AM Lecce station | 1 transfer | |
Regionale 19970+ Autobus FS Sud Est 56219 | 7:01 AM Mesagne | 1h59 | 9:00 AM Lecce, Palazzetto Dello Sport | 1 transfer | |
Regionale 4385+ Autobus FS Sud Est 50056 | 7:10 AM Mesagne, Cittadella Della Ricerca | 2h05 | 9:15 AM Lecce station | 1 transfer | |
Regionale Veloce 4401+ Autobus FS Sud Est 50084 | 11:45 AM Mesagne | 2h28 | 2:13 PM Lecce station | 1 transfer | |
Autobus FS Sud Est 54006 · Autobus FS Sud Est 35099 | 2:50 PM Mesagne | 1h25 | 4:15 PM Lecce, Palazzetto Dello Sport | 1 transfer | |
Autobus FS Sud Est 50077 · Autobus FS Sud Est 715B | 3:15 PM Mesagne, Cittadella Della Ricerca | 3h38 | 6:53 PM Lecce station | 1 transfer | |
Intercity 603+ Autobus FS Sud Est 50114 | 3:15 PM Mesagne | 1h36 | 4:51 PM Lecce station | 1 transfer | |
Regionale Veloce 4421+ Autobus FS Sud Est 50118 | 4:30 PM Mesagne | 1h43 | 6:13 PM Lecce station | 1 transfer | |
Regionale 19982+ Autobus FS Sud Est 717B | 6:21 PM Brindisi Cittadella Della Ricerca | 2h14 | 8:35 PM Lecce station | 1 transfer | |
Regionale Veloce 4429+ Autobus FS Sud Est 50122 | 6:25 PM Mesagne | 1h48 | 8:13 PM Lecce station | 1 transfer | |
Regionale 19982+ Autobus FS Sud Est 717B | 6:25 PM Mesagne | 2h10 | 8:35 PM Lecce station | 1 transfer | |
Regionale 4439+ Autobus FS Sud Est 50124 | 7:55 PM Mesagne | 2h30 | 10:25 PM Lecce station | 1 transfer | |
FRECCIAROSSA 8317+ Autobus FS Sud Est 50124 | 7:55 PM Mesagne | 1h53 | 9:48 PM Lecce station | 1 transfer | |
Regionale 19984+ Autobus FS Sud Est 719B | 8:28 PM Brindisi Cittadella Della Ricerca | 2h20 | 10:48 PM Lecce station | 1 transfer | |
Regionale 19984+ Autobus FS Sud Est 719B | 8:32 PM Mesagne | 2h16 | 10:48 PM Lecce station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Lecce — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lecce trip today.
Major museum of Apulian archaeology with Messapian, Roman, and medieval finds. Essential for understanding Lecce and Salento before exploring the city.
Museum of the Roman theatre area displaying excavated sculptures, inscriptions, and models. A useful companion to Lecce's visible ancient remains.
Contemporary art museum in a former monastery with rotating exhibitions and cultural events. A strong stop for modern creativity in historic Lecce.
Lecce's main square with the Roman amphitheatre, civic landmarks, and constant street life. The best starting point for understanding the city center.
Enclosed cathedral square of rare theatrical beauty, framed by the duomo, bell tower, and seminary. One of southern Italy's finest urban spaces.
The maze-like historic center of Lecce, rich in Baroque churches, carved balconies, and artisan workshops. Best explored slowly on foot.
Rustic shortcrust pastry filled with tomato, mozzarella and béchamel. A beloved Lecce street snack, especially from local bakeries and bars.
Fresh pasta shaped like twisted ribbons, often served with rich tomato sauce and ricotta forte or caciotta. A classic Salento homemade dish.
Fried potato croquettes stuffed with mozzarella and sometimes tomato. Popular in Lecce rotisserie shops as a comforting local snack.
Elegant Michelin-starred restaurant known for refined Salento cuisine in a historic setting near the old city.
Historic, casual spot famous for rustic Salento cooking, generous portions and a lively local dining room.
Long-established Lecce institution serving traditional Salento dishes and seafood in a polished yet welcoming atmosphere.
Moderate for Italy: dining is reasonable, local transit is low-cost, and lodging is often cheaper than Rome, Milan, or Florence, though summer rates rise in the historic center.
Tipping is modest. A service charge may appear. Round up or leave 5-10% at restaurants for great service; round up taxi fares; small change is fine at cafes.
Find answers to the most common questions about traveling from Mesagne to Lecce by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lecce, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need