- Must visit
Pima Air & Space Museum
World-renowned aviation museum with historic aircraft, hangars, and restoration spaces on a vast desert campus.
The best way to find a cheap bus ticket from Mesa, AZ to Tucson, AZ is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mesa, AZ to Tucson, AZ will cost around €24 if you buy it on the day, but the cheapest tickets can be found for only €24.
On Wed, Nov 04, we found 1 buses from Mesa, AZ to Tucson, AZ, including 1 direct services.
On Wed, Nov 04 the direct buses cover the 158 km distance in an average of 2 h but if you time it right, some buses will get you there in just 2 h .
On Wed, Nov 04 the slowest buses will take 2 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Mesa, AZ to Tucson, AZ run on average 4 times per day, taking around 1h 44m. Cheap bus tickets for this journey start at €19 if you book in advance.
There are 4 buses per day. The earliest bus runs at 00:09, the last at 23:15. The fastest bus covers the 98 miles (158 km) distance in 1h 30m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Mesa, AZ to Tucson, AZ.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:15AM | Arrival Time 03:15AM | Duration 2h00 | Departure days Sat, Sun | Cheapest price €28 |
Operator Greyhound | Departure Time 02:15AM | Arrival Time 04:15AM | Duration 2h00 | Departure days Wed, Fri, Sat | Cheapest price €24 |
Operator Greyhound | Departure Time 10:50AM | Arrival Time 12:35PM | Duration 1h45 | Departure days Sat | Cheapest price €21 |
The table below shows live departures for Mesa, AZ to Tucson, AZ buses for tomorrow, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:15 AM Mesa, AZ | 2h00 | 4:15 AM Tucson, AZ | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Mesa, AZ to Tucson, AZ with Tufesa Internacional, Greyhound, and FlixBus. Overnight buses available on this route with Greyhound and FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Tucson, AZ — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Tucson, AZ trip today.
World-renowned aviation museum with historic aircraft, hangars, and restoration spaces on a vast desert campus.
University art museum with strong Latin American, modern, and contemporary collections in a compact campus setting.
Interactive science museum for all ages with hands-on exhibits, planetarium, and rotating educational displays.
Popular mountain park with desert trails, giant cacti, and summit road views over Tucson and surrounding ranges.
Walkable historic district with adobe architecture, shops, galleries, and some of Tucson's oldest streetscapes.
Scenic desert road and trail area in Saguaro National Park West, famous for sunset drives and iconic cactus views.
A Sonoran-style hot dog wrapped in bacon and topped with beans, onions, tomato, mustard, mayo, and jalapeño sauce. A Tucson street-food icon tied to regional Mexican roots.
Carne seca is thin beef dried in the desert tradition, then often shredded and cooked with eggs or chiles. It reflects Tucson’s ranching and borderlands heritage.
A wheat tortilla folded around cheese and often grilled over mesquite. This regional staple shows Tucson’s long flour-tortilla tradition rooted in Sonoran cuisine.
Upscale destination for creative desert cuisine using Native and regional ingredients. Stylish setting with a strong focus on Tucson terroir.
Refined Southwestern dining at Hacienda Del Sol, known for regional ingredients, polished service, and a romantic desert setting.
Historic casual spot famous for Sonoran hot dogs and other Tucson staples. Lively, unfussy, and one of the city’s best-known local institutions.
Moderate for a US city. Hotels are often cheaper than major US hubs; dining is reasonable, but car use and limited transit can raise visitor costs.
Tip 18-20% in restaurants, more for great service. Taxis usually 10-15%. Round up or tip $1-2 at cafes.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Tucson, AZ.
Find answers to the most common questions about traveling from Mesa, AZ to Tucson, AZ by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tucson, AZ, this guide helps you travel smarter and with confidence.

Most Mesa, AZ to Tucson, AZ buses use the Mesa, South Country Club Drive (Greyhound Bus Station) to Tucson, E 12th St (Bus Station) station pair, with some services arriving at Tuscon, University of Arizona Transportation Office. Use this guide to compare Mesa, AZ and Tucson, AZ bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Mesa, South Country Club Drive (Greyhound Bus Station) is 4 km from Mesa city centre. Public transport options include:
Mesa, South Country Club Drive (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi available inside the station. ATMs are available at Mesa, South Country Club Drive (Greyhound Bus Station).
Ticket office support is available at Mesa, South Country Club Drive (Greyhound Bus Station).
Available at Mesa, South Country Club Drive (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Mesa, South Country Club Drive (Greyhound Bus Station): Station is wheelchair accessible.
Tucson, E 12th St (Bus Station) is 3 km from Tucson city centre. Public transport options include:
Tucson, E 12th St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Tucson, E 12th St (Bus Station). ATMs are available at Tucson, E 12th St (Bus Station).
Ticket office support is available at Tucson, E 12th St (Bus Station).
Available at Tucson, E 12th St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Tucson, E 12th St (Bus Station): Basic accessibility features available.
Tuscon, University of Arizona Transportation Office is 2 km from Tucson city centre. Public transport options include:
Tuscon, University of Arizona Transportation Office has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available for visitors. ATMs are available at Tuscon, University of Arizona Transportation Office.
Ticket office support is available at Tuscon, University of Arizona Transportation Office.
Available at Tuscon, University of Arizona Transportation Office: Parking, Taxis, WC.
Accessibility facilities are available at Tuscon, University of Arizona Transportation Office: Facility is wheelchair accessible.
Tucson, Downtown is 3 km from Tucson city centre. Public transport options include:
Tucson, Downtown has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Food vendors nearby.
Free public Wi-Fi available. ATMs are available at Tucson, Downtown.
Ticket office support is available at Tucson, Downtown.
Available at Tucson, Downtown: Parking, Taxis, WC.
Accessibility facilities are available at Tucson, Downtown: Wheelchair accessible facilities available.
Check bus stations information for Mesa, AZ and Tucson, AZ, including where buses depart and arrive on this route.