- Must visit
Pima Air & Space Museum
World-renowned aviation museum with historic aircraft, hangars, and restoration spaces on a vast desert campus.
We are not able to find a bus between these two places.
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Omio recommends booking the bus as it is the most popular option from Mesa, AZ to Tucson, AZ among Omio's users. If you are prioritising price take the bus with prices starting from $25. For those with little time consider booking a flight which can get you there in 56m. The ticket price range depends on the travel mode: a bus costs an average of $25, and a flight costs an average of $330.
Distance: 98 miles (158 km)
Most popular Bus | Flight | Train |
|---|---|---|
$33 Average price Cheapest | $391 Average price | $75 Average price |
2h 30m Average total duration 2h 0m Onboard + 30m Additional time* | 3h 56m Average total duration Fastest 56m Onboard + 3h 0m Additional time* | 3h 38m Average total duration 3h 8m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Mesa, AZ to Tucson, AZ:
A bus is $41 (€34) less than a train for this route with tickets for a train from Mesa, AZ to Tucson, AZ costing on average $75 (€61).
A bus is $358 (€294) less than a flight for this route with tickets for a flight from Mesa, AZ to Tucson, AZ costing on average $391 (€321).
Other travel options to Tucson, AZ take longer:
Bus takes on average 2h 0m.
Train takes on average 3h 8m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:15AM | Arrival Time 03:15AM | Duration 2h00 | Departure days Sat, Sun | Cheapest price $34 |
Operator Greyhound | Departure Time 02:15AM | Arrival Time 04:15AM | Duration 2h00 | Departure days Wed, Fri, Sat | Cheapest price $29 |
Operator Greyhound | Departure Time 10:50AM | Arrival Time 12:35PM | Duration 1h45 | Departure days Sat | Cheapest price $25 |
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Mesa, AZ to Tucson, AZ run on average 3 times per day, taking around 2h 0m. Cheap bus tickets for this journey start at $25 (€20) if you book in advance.
There are 2 buses per day. The earliest bus runs at 00:09, the last at 23:15. The fastest bus covers the 98 miles (158 km) distance in 1h 45m.
Distance 98 miles (158 km) |
Average bus duration 2h 0m |
Cheapest ticket price $25 (€20) |
Buses per day 3 |
Direct buses 2 |
Fastest bus 1h 45m |
First bus 12:09 AM |
Last bus 11:15 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Jan - Mar |
Discover the best of Tucson, AZ — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Tucson, AZ trip today.
World-renowned aviation museum with historic aircraft, hangars, and restoration spaces on a vast desert campus.
University art museum with strong Latin American, modern, and contemporary collections in a compact campus setting.
Interactive science museum for all ages with hands-on exhibits, planetarium, and rotating educational displays.
Popular mountain park with desert trails, giant cacti, and summit road views over Tucson and surrounding ranges.
Walkable historic district with adobe architecture, shops, galleries, and some of Tucson's oldest streetscapes.
Scenic desert road and trail area in Saguaro National Park West, famous for sunset drives and iconic cactus views.
A Sonoran-style hot dog wrapped in bacon and topped with beans, onions, tomato, mustard, mayo, and jalapeño sauce. A Tucson street-food icon tied to regional Mexican roots.
Carne seca is thin beef dried in the desert tradition, then often shredded and cooked with eggs or chiles. It reflects Tucson’s ranching and borderlands heritage.
A wheat tortilla folded around cheese and often grilled over mesquite. This regional staple shows Tucson’s long flour-tortilla tradition rooted in Sonoran cuisine.
Upscale destination for creative desert cuisine using Native and regional ingredients. Stylish setting with a strong focus on Tucson terroir.
Refined Southwestern dining at Hacienda Del Sol, known for regional ingredients, polished service, and a romantic desert setting.
Historic casual spot famous for Sonoran hot dogs and other Tucson staples. Lively, unfussy, and one of the city’s best-known local institutions.
Moderate for a US city. Hotels are often cheaper than major US hubs; dining is reasonable, but car use and limited transit can raise visitor costs.
Tip 18-20% in restaurants, more for great service. Taxis usually 10-15%. Round up or tip $1-2 at cafes.
Find answers to the most common questions about traveling from Mesa, AZ to Tucson, AZ by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tucson, AZ, this guide helps you travel smarter and with confidence.

Most Mesa, AZ to Tucson, AZ buses use the Mesa, South Country Club Drive (Greyhound Bus Station) to Tucson, E 12th St (Bus Station) station pair, with some services arriving at Tuscon, University of Arizona Transportation Office. Use this guide to compare Mesa, AZ and Tucson, AZ bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need