Compare prices and tickets Medford, OR to Portland, OR by flight
Compare flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Medford, OR to Portland, OR buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Medford, OR to Portland, OR
Take a bus from Medford, OR to Portland, OR and enjoy the approximately 221 miles (356 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
There are 1 buses per day. The earliest bus runs at 02:00, the last at 16:20.
Distance 221 miles (356 km) |
Average bus duration 5h 25m |
Buses per day 1 |
Direct buses 1 |
First bus 02:00 |
Last bus 16:20 |
Cheapest month May |
Cheapest day Tue |
High season Jul - Sep |
Low season Jan - Mar |
Busiest day Fri |
Least busy day Fri |
Bus providers: Greyhound from Medford, OR to Portland, ORYou can travel by bus between Medford, OR to Portland, OR with Greyhound for as low as $99 (€80). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Medford, OR to Portland, OR
Find answers to the most common questions about traveling from Medford, OR to Portland, OR by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Portland, OR, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Portland Japanese Garden, a tranquil 12-acre garden offering traditional Japanese landscaping and cultural events
- Powell's City of Books, the world's largest independent bookstore spanning an entire city block
- Washington Park, a large urban park featuring a zoo, rose garden, and hiking trails
- Pittock Mansion, a historic house museum with panoramic views of Portland and the surrounding mountains
- Lan Su Chinese Garden, a classical Chinese garden in the heart of the city showcasing authentic design and architecture.
- Portland Art Museum, a prominent museum showcasing diverse art collections and rotating exhibitions
- Voodoo Doughnut, a quirky doughnut shop famous for its creative and unconventional doughnut flavors
- Forest Park, one of the largest urban forests in the U.S., offering extensive hiking and biking trails
- OMSI (Oregon Museum of Science and Industry), an interactive science museum with exhibits and a planetarium
- Portland Saturday Market, a vibrant open-air market featuring local artisans, food vendors, and live entertainment.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Medford, OR to Portland, OR
Most popular bus connections from Medford, OR
More options for your journey from Medford, OR to Portland, OR
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