- Must visit
Pinacoteca di Brera
One of Italy’s leading art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the elegant Brera district.
Cheapest price
$47
Average price
$56
Fastest journey
13 h 50 m
Average duration
15 h 30 m
Buses per day
2
Distance
689 km
The best way to find a cheap bus ticket from Manfredonia to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Manfredonia to Milan will cost around $56 if you buy it on the day, but the cheapest tickets can be found for only $47.
Of the 2 buses that leave Manfredonia for Milan on Mon, Jun 01, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jun 01 the direct buses cover the 689 km distance in an average of 15 h 30 m but if you time it right, some buses will get you there in just 13 h 50 m .
On Mon, Jun 01 the slowest buses will take 17 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the bus as it is the most popular option from Manfredonia to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $22. For those with little time consider booking a flight which can get you there in 1h 38m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $22, and a flight costs an average of $24.
Distance: 428 miles (689 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$62 Average price Cheapest | $115 Average price | $106 Average price | $235 Average price (fuel + tolls) |
10h 24m Average total duration 9h 54m Onboard + 30m Additional time* | 4h 38m Average total duration Fastest 1h 38m Onboard + 3h 0m Additional time* | 7h 55m Average total duration 7h 25m Onboard + 30m Additional time* | 8h 17m Average total duration (door-to-door) |
0.7 - 1.7kg CO2 emissions | 2.1 - 4.1kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Manfredonia to Milan:
A bus is $44 (€35) less than a train for this route with tickets for a train from Manfredonia to Milan costing on average $106 (€85).
A bus is $52 (€42) less than a flight for this route with tickets for a flight from Manfredonia to Milan costing on average $115 (€93).
Other travel options to Milan take longer:
Train takes on average 7h 25m.
Bus takes on average 9h 54m.
Tickets start at around $62 (€50) compared to roughly $235 (€189) in fuel and tolls — a saving of about $172 (€139). The journey takes 9h 54m versus 8h 17m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:05AM | Arrival Time 01:25PM | Duration 13h20 | Departure days Mon | Cheapest price $73 |
Operator FlixBus | Departure Time 05:10AM | Arrival Time 09:35PM | Duration 16h25 | Departure days Wed, Thu, Fri, Sat | Cheapest price $59 |
Operator FlixBus | Departure Time 06:10AM | Arrival Time 06:55PM | Duration 12h45 | Departure days Thu | Cheapest price $38 |
Operator FlixBus | Departure Time 06:15AM | Arrival Time 06:55PM | Duration 12h40 | Departure days Wed, Thu, Fri | Cheapest price $22 |
Operator FlixBus | Departure Time 07:10AM | Arrival Time 08:45PM | Duration 13h35 | Departure days Mon, Tue | Cheapest price $74 |
Operator Marino Autolinee | Departure Time 07:55AM | Arrival Time 06:40PM | Duration 10h45 | Departure days Mon, Tue | Cheapest price $87 |
Operator BlaBlaCar | Departure Time 12:50PM | Arrival Time 08:10PM | Duration 7h20 | Departure days Tue | Cheapest price $79 |
Operator Ferrovie del Gargano | Departure Time 05:45PM | Arrival Time 04:15AM | Duration 10h30 | Departure days Wed, Fri | Cheapest price $94 |
Operator Ferrovie del Gargano | Departure Time 06:45PM | Arrival Time 05:15AM | Duration 10h30 | Departure days Fri, Sat | Cheapest price $84 |
Operator Marino Autolinee | Departure Time 08:30PM | Arrival Time 06:25AM | Duration 9h55 | Departure days Mon, Tue | Cheapest price $97 |
Operator FlixBus | Departure Time 10:05PM | Arrival Time 03:15PM | Duration 17h10 | Departure days Wed, Thu, Sat | Cheapest price $65 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 12:55PM | Duration 13h50 | Departure days Thu, Fri, Sat | Cheapest price $40 |
The table below shows live departures for Manfredonia to Milan buses for today, Saturday, May 30. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:45 PM Manfredonia | 10h30 | 5:15 AM Milan | 0 transfersDirect | |
![]() | 11:05 PM Manfredonia | 13h50 | 12:55 PM Milan | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Manfredonia to Milan run on average 10 times per day, taking around 9h 54m. Cheap bus tickets for this journey start at $22 (€18) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 23:50. The fastest bus covers the 428 miles (689 km) distance in 10h 30m.
Distance 428 miles (689 km) |
Average bus duration 9h 54m |
Cheapest ticket price $22 (€18) |
Buses per day 10 |
Direct buses 1 |
Fastest bus 10h 30m |
First bus 12:05 AM |
Last bus 11:50 PM |
Cheapest Month May |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 42 days |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
One of Italy’s leading art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the elegant Brera district.
A major museum of 20th-century Italian art facing Piazza del Duomo, with strong Futurist holdings and striking city views.
A contemporary museum focused on world cultures and major temporary exhibitions, popular for its modern architecture and changing shows.
Milan’s canal district, best known for waterside walks, photogenic bridges, and lively atmosphere day and night.
A charming historic neighborhood of narrow streets, galleries, boutiques, and classic Milan character, ideal for wandering.
Milan’s main square and the symbolic heart of the city, surrounded by major landmarks and constant urban energy.
Creamy saffron risotto, one of Milan's signature dishes, prized for its rich flavor and golden color.
Braised veal shank cooked slowly until tender, traditionally served with gremolata and often paired with risotto.
Breaded veal cutlet fried in butter, a classic Milanese specialty and one of the city's most famous dishes.
Celebrated fine dining restaurant offering creative haute cuisine with an elegant, Michelin-starred reputation.
Famous central bakery known for panzerotti, a beloved casual stop near the Duomo with constant local appeal.
Modern Milanese restaurant known for refined Lombard classics in a stylish contemporary setting.
Milan is pricier than most Italian cities, especially for hotels, central dining, and aperitivo areas.
Service is often included or covered by coperto. Tipping is not required, but rounding up or leaving EUR 1-5 for good service is appreciated. Taxis can be rounded up.
Official public transport app
Milan Linate Airport, Milan -> Milano Centrale, Milan
Find answers to the most common questions about traveling from Manfredonia to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

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