Prague to Brussels train with České dráhy

Mon, 28 Sept
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Alibus
Deutsche Bahn
České dráhy
SNCF | TGV INOUI
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Alibus
Deutsche Bahn
České dráhy
SNCF | TGV INOUI
Italo
2,000+ travel companies
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The cheapest and fastest trains from Prague to Brussels

Showing times, prices and bookable tickets for 28 Sept

Cheapest price on 28 Sept

69฿

Average ticket price on 28 Sept

120฿

Fastest journey on 28 Sept

11 h

Average journey duration on 28 Sept

11 h 25 m

Trains on 28 Sept

14

Distance

717 km

Cheap tickets

The best way to find a cheap train ticket from Prague to Brussels is to book your journey as far in advance as possible and to avoid travelling at rush hour.

The average ticket from Prague to Brussels will cost around 120฿ if you buy it on the day, but you can find cheap train tickets today for only 69฿.

Fast trains

To travel from Prague to Brussels you need to make at least 2 changes.

  • Deutsche BahnIC 562 · 5288 · IC 2066 · ICE 1090
    12:35 PM18h53
    Prague hlavní nádraží
    7:28 AMBrussels-Midi
    69 ฿1One-way
    6 changes
  • Deutsche BahnRJ 512 · 5286 · ICE 622 · ICE 10
    10:35 AM11h00
    Prague hlavní nádraží
    9:35 PMBrussels-Midi
    74 ฿1One-way
    3 changes
  • Deutsche BahnIC 562 · 5288 · ICE 528 · 26834
    12:35 PM17h12
    Prague hlavní nádraží
    5:47 AMBrussels-Midi
    80 ฿1One-way
    5 changes
  • Deutsche BahnIC 564 · 5284 · ICE 626 · ICE 12
    8:35 AM11h00
    Prague hlavní nádraží
    7:35 PMBrussels-Midi
    86 ฿1One-way
    3 changes
  • Deutsche BahnRJ 382 · BUS 10382 · ICE 1556 · ICE 514
    10:31 AM13h56
    Prague hlavní nádraží
    12:27 AMBrussels-Midi
    91 ฿1One-way
    6 changes

Live departures

Prague to Brussels train times

The table below shows live departures for Prague to Brussels trains for today, Sunday, 27 September. You can also manually refresh the results below to see updated train journeys.

Last updated at
ProviderDepartsDurationArrivesChanges
Tickets
Alibus4526:00 PM Prague hlavní nádraží
15h27
9:27 AM Brussels-Midi0 changesdirect
Alibus4526:00 PM Prague hlavní nádraží
15h52
9:52 AM Brussels-Midi0 changesdirect
Monday, 28 September
Deutsche BahnRJ 384 · ICE 650 · ICE 14
On time
6:31 AM Prague hlavní nádraží
11h04
5:35 PM Brussels-Midi
2 changes
Deutsche BahnEX 360 · 3564 · ICE 626 · ICE 12
On time
7:35 AM Prague hlavní nádraží
12h00
7:35 PM Brussels-Midi
3 changes
Deutsche BahnEX 360 · 3564 · ICE 626 · ICE 12
On time
7:35 AM Prague hlavní nádraží
12h00
7:35 PM Brussels-Midi
3 changes
Deutsche BahnIC 564 · 5284 · ICE 626 · ICE 12
On time
8:35 AM Prague hlavní nádraží
11h00
7:35 PM Brussels-Midi
3 changes
Deutsche BahnEX 358 · 3568 · ICE 622 · ICE 10
On time
9:35 AM Prague hlavní nádraží
12h00
9:35 PM Brussels-Midi
3 changes
Deutsche BahnEX 358 · 3570 · ICE 622 · ICE 10
On time
9:35 AM Prague hlavní nádraží
12h00
9:35 PM Brussels-Midi
3 changes
Deutsche BahnRJ 382 · BUS 10382 · IC 2176 · 2189410:31 AM Prague hlavní nádraží
13h46
12:17 AM Brussels-Midi9 changes
Deutsche BahnRJ 382 · BUS 10382 · IC 2176 · 2189410:31 AM Prague hlavní nádraží
13h40
12:11 AM Brussels-Midi10 changes
Deutsche BahnRJ 382 · BUS 10382 · ICE 1556 · ICE 51410:31 AM Prague hlavní nádraží
13h56
12:27 AM Brussels-Midi6 changes
Deutsche BahnRJ 382 · BUS 10382 · ICE 1556 · ICE 51410:31 AM Prague hlavní nádraží
13h56
12:27 AM Brussels-Midi6 changes
Deutsche BahnRJ 512 · 5286 · ICE 622 · ICE 10
On time
10:35 AM Prague hlavní nádraží
11h00
9:35 PM Brussels-Midi
3 changes
Deutsche BahnEX 356 · ICE 512 · 26834 · 18978
On time
11:35 AM Prague hlavní nádraží
18h12
5:47 AM Brussels-Midi
4 changes
Deutsche BahnIC 562 · 5288 · ICE 528 · 2683412:35 PM Prague hlavní nádraží
17h12
5:47 AM Brussels-Midi5 changes
Deutsche BahnIC 562 · 5288 · IC 2066 · ICE 109012:35 PM Prague hlavní nádraží
18h53
7:28 AM Brussels-Midi6 changes

This is the last train of the day.

Find all the dates and times for this journey

Compare prices and tickets Prague to Brussels by coach, train or flight

Compare coach, train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Prague to Brussels trains with Omio?

Alibus as well as Deutsche Bahn or České dráhy offer trains services from Prague to Brussels.
Omio is an official ticket reseller for all your travel options from Prague to Brussels.

Why book with Omio vs Alibus?

  • Compare with other providers: On Omio, you can not only buy tickets for Alibus, but also compare tickets for the likes of Deutsche Bahn or České dráhy to find the best option for your trip from Prague to Brussels.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Alibus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Prague to Brussels.

Why book with Omio over Wanderu, Trainline or Raileurope?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Deutsche Bahn or České dráhy to find the best option for your trip from Prague to Brussels.
  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Prague to Brussels.

How far in advance should I book train tickets from Prague to Brussels?

The best time to book your train from Prague to Brussels is 77 days before departure. See how prices for trains change on the Prague to Brussels route.
Prices are for one-way tickets for one passenger from Prague to Brussels per month. Insights are sourced from fares found by Omio users in the last 12 months. Current prices may differ as prices vary depending on the time of day, class or how far in advance you book your train from Prague to Brussels.

Journey information

Overview: Train from Prague to Brussels

CzechiaCzechia
BelgiumBelgium
Icon of train

Trains from Prague to Brussels run on average 8 times per day, taking around 10h 52m. Cheap train tickets for this journey start at 13฿ if you book in advance.

The earliest train runs at 00:10, the last at 23:55. The fastest train covers the 717 km distance in 9h 13m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
717 km
Average train duration
10h 52m
Cheapest ticket price
13฿
Trains per day
8
Fastest train
9h 13m
First train
12:10 AM
Last train
11:55 PM
Cheapest Month
Aug
Cheapest Day
Thu
High Season
Oct - Dec
Low Season
Jan - Mar
Busiest Day
Wed
Least Busy Day
Sat
Best time to book
84 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Train companies: České dráhy, Deutsche Bahn, Alibus from Prague to Brussels trainsČeské dráhy, Deutsche Bahn, Alibus trains will get you between Prague and Brussels from 13฿. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Deutsche Bahn

About
Deutsche Bahn (DB) is Germany’s main train operator, running around 40,000 domestic and international services each day. Its fleet includes a variety of train types: high-speed ICE (Intercity Express) trains, reaching up to 300 km/h; IC (Intercity) and EC (EuroCity) trains for long-distance travel; and IRE (Interregio-Express), RE (Regional Express), and RB (Regionalbahn) services for regional and local connections. While bathrooms are standard on all trains, amenities such as onboard restaurants and free Wi-Fi are available only on certain train types and routes. DB offers a wide range of fares, including Super Saver, Saver, and Flexible tickets, along with discount cards like the BahnCard 25, 50, and 100. Additional options include single tickets, day tickets, and group tickets. Popular routes include Berlin–Munich, Hamburg–Frankfurt, Cologne–Stuttgart, Berlin–Dresden, and Hamburg–Cologne, as well as numerous regional services across Germany.
Luggage & cancellation policy
Average Deutsche Bahn Duration
9h 22m
Cheapest Deutsche Bahn Price
45฿
Deutsche Bahn frequency
4 a day
Luggage included
Passengers are allowed to bring hand luggage and one additional larger item free of charge, provided they can carry it themselves
Luggage storage
Luggage can be stored in overhead racks, under the seat, or in designated luggage areas near the doors or in the middle of the carriage.
Cancellation Policy
Tickets can be canceled based on their fare conditions as mentioned in what type of train tickets are refundable?
Refund
If DB cancels a train, passengers are entitled to a full refund of the ticket price.
Amenities on board the train
Wifi
Food sold onboard
Most ICE and many IC/EC trains have:
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Seat reservation
Second Class:
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Toilets
USB plugs
Accessibility
DB trains are equipped with facilities for passengers with reduced mobility, including wheelchair spaces, accessible restrooms, and assistance services.
Pets
Small pets (e.g. cats, small dogs, etc.):
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Quiet zone

Alibus

About
European Sleeper is a Belgian-Dutch train company launched in 2021, operating night train services between Germany and Belgium three times a week, with plans to expand to daily service and extend routes to cities such as Dresden and Prague. Passengers can choose from standard seats, couchettes, or sleeper cabins. Couchettes include free drinks and power outlets, while sleeper cabins offer power outlets and complimentary meals. All tickets are sold as Flex Night fares, which are non-exchangeable but can be canceled up to 48 hours before departure.
Luggage & cancellation policy
Average Alibus Duration
14h 33m
Cheapest Alibus Price
40฿
Alibus frequency
1 a day
Luggage included
1 piece of hand luggage and 2 pieces of hold luggage included in ticket price
Luggage storage
Luggage racks above seats and at end of carriages
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car serving breakfast, drinks and snacks available for purchase
Seat reservation
Seat or berth reservation mandatory and included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces available, accessible toilets, staff assistance
Pets
Small pets in carriers allowed for free, larger dogs require paid ticket
Quiet zone

České dráhy

About
Czech Railways (České dráhy, ČD) is the largest railway company in the Czech Republic, connecting major cities, small towns, and even international destinations across Europe. Its extensive fleet of modern trains ranges from comfortable regional services with A/C and onboard WiFi to high-speed trains offering dining cars, power outlets, and premium seating for long-distance journeys. Czech Railways combines affordability and convenience, making it a popular choice for travelers exploring the Czech Republic and beyond.
Luggage & cancellation policy
Average České dráhy Duration
9h 13m
Cheapest České dráhy Price
13฿
České dráhy frequency
5 a day

FAQs: Prague to Brussels train

Find answers to the most common questions about traveling from Prague to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

FAQs
Cheap train tickets from Prague to Brussels can start from as little as 13฿ when you book in advance. The average train ticket price for Prague to Brussels is 157฿; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by train from Prague to Brussels is 9h 13m to travel the 717 km long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest train from Prague to Brussels leaves at 12:10 am. Plan your trip with the Journey Planner from Omio.
The latest train from Prague to Brussels leaves at 11:55 pm.
There are 8 trains a day from Prague to Brussels which require at least one change with Alibus, Deutsche Bahn, České dráhy. Schedules can vary on holidays or weekends with fewer trains.
When taking a train from Prague to Brussels, you can count on Alibus, Deutsche Bahn, České dráhy for the best way to get you to Brussels. You can also check all possible train companies who offer a service between Prague and Brussels and compare the amenities they offer before buying a train ticket.
Yes, you can take a night train from Prague to Brussels with Alibus. Find all the info regarding night trains in Europe.
A trip to Brussels from Prague is worth doing but not as a day trip with a journey time of 9h 13m each way. Check with Omio app the best way to travel.
It's helpful to compare your options as there are 3 ways to travel between Prague and Brussels including taking a coach, train and flight.

popular train stations

Important Stations and Airports in Prague and Brussels

Most Prague to Brussels trains use the Praha hlavní nádraží to Bruxelles-Midi station pair, with some services arriving at Bruxelles-Central. Use this guide to compare Prague and Brussels train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.

Departure train stations in Prague
Arrival train stations in Brussels

Which Prague station do trains to Brussels leave from?

Trains from Prague to Brussels leave from Praha hlavní nádraží. The station is 1 km from Prague city centre at Wilsonova 300/8, 120 00 Praha 2, Czechia.
Praha hlavní nádražíWilsonova 300/8, 120 00 Praha 2, Czechia+420 221 111 122WifiLockersParkingDiningATMTaxisAccessibilityWCHotelShowerLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation DeskLuggage Carts
City-centre transport

Getting to Praha hlavní nádraží from Prague city centre

Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:

TrainRj, 600, 602, 604, 606, 608, 610, 612, 614, 616, 618, 670, 674, 676, 678, 680, 682, 684, 686, 688, 690, 692, 694, 696, 698, 2474, Re · 8m · 1฿ · every ~3 min
Nj · 8m · 14฿
Bus478 · 5m
Tram17, 93 · 10m · 2฿ · every ~23 min
17, 93 · 12m · 2฿ · every ~23 min
SubwayC · 5m · 2฿ · every ~29 min

Praha hlavní nádraží train station facilities and services

Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk and Luggage Carts.

Food and drink

Food options include: Restaurant Fantova Kavárna, Sushi Time

Wi-Fi and ATMs

Free. ATMs are available in the train station.

Tickets and information

Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.

Luggage and lost property

Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.

Parking, taxis and toilets

Available at Praha hlavní nádraží: Parking, Taxis, WC.

Bike and car services

Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.

Accessibility

Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.

Shops, hotels and contact

Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.

Praha-HolesovicePartyzánská 26, Holesovice, Prague 7, Czechia+420 296 191 817WifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation DeskLuggage Carts
City-centre transport

Getting to Praha-Holesovice from Prague city centre

Praha-Holesovice is 2 km from Prague city centre. Public transport options include:

TrainRj, 600, 602, 604, 606, 608, 610, 612, 614, 616, 618, 670, 674, 676, 678, 680, 682, 684, 686, 688, 690, 692, 694, 696, 698, 2474, Re · 8m · 1฿ · every ~3 min
Nj · 8m · 14฿
Bus478 · 5m
Tram17, 93 · 10m · 2฿ · every ~23 min
17, 93 · 12m · 2฿ · every ~23 min
SubwayC · 5m · 2฿ · every ~29 min

Praha-Holesovice train station facilities and services

Praha-Holesovice has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk and Luggage Carts.

Food and drink

Food options include: Restaurant Na Kovárně, Cross Club

Wi-Fi and ATMs

Free. ATMs are available in the train station.

Tickets and information

Ticket office support is available at Praha-Holesovice. Information desks are located in the main hall.

Luggage and lost property

Luggage storage is available at Praha-Holesovice. Lost and found is available at the station.

Parking, taxis and toilets

Available at Praha-Holesovice: Parking, Taxis, WC.

Bike and car services

Available at Praha-Holesovice: Bike Parking, Bike Rental, Car Rental.

Accessibility

Accessibility facilities are available at Praha-Holesovice: Ramps, restrooms.

Shops, hotels and contact

Nearby hotels include Mama Shelter Prague, Plaza Alta Hotel, Hotel Belvedere.

Praha Masarykovo NádražíHybernská 1014/13, 110 00 Praha 1, Czechia+420 221 111 122WifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation DeskLuggage Carts
City-centre transport

Getting to Praha Masarykovo Nádraží from Prague city centre

Tram15, 22 · 14m · 2฿ · every ~12 min

Praha Masarykovo Nádraží train station facilities and services

Praha Masarykovo Nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk and Luggage Carts.

Food and drink

Food options include: Restaurant Kotleta, Café Imperial

Wi-Fi and ATMs

Free. ATMs are available in the train station.

Tickets and information

Ticket office support is available at Praha Masarykovo Nádraží. Information desks are located in the main hall.

Luggage and lost property

Luggage storage is available at Praha Masarykovo Nádraží. Lost and found is available at the station.

Parking, taxis and toilets

Available at Praha Masarykovo Nádraží: Parking, Taxis, WC.

Bike and car services

Available at Praha Masarykovo Nádraží: Bike Parking, Bike Rental, Car Rental.

Accessibility

Accessibility facilities are available at Praha Masarykovo Nádraží: Ramps.

Shops, hotels and contact

Nearby hotels include Hotel Kings Court, Grand Hotel Bohemia, Hotel Paris Prague.

More options for your journey from Prague to Brussels

Here are some other resources that might have the information you need

HomeTrainsTrains in BelgiumPrague to Brussels train

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