The cheapest and fastest trains from Luxembourg to Prague
Cheapest price on 28 Sept
79S$
Average ticket price on 28 Sept
208S$
Fastest journey on 28 Sept
11 h 10 m
Average journey duration on 28 Sept
11 h 34 m
Trains on 28 Sept
19
Distance
596 km
The best way to find a cheap train ticket from Luxembourg to Prague is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Luxembourg to Prague will cost around 208S$ if you buy it on the day, but you can find cheap train tickets today for only 79S$.
To travel from Luxembourg to Prague you need to make at least 4 changes.
Bus 82158 · 4132 · EC 4598:05 PM13h20Luxembourg station9:25 AMPrague hlavní nádraží79 S$1One-way2 changes
Bus 82150 · 4122 · ICE 590 · 165016:10 PM15h00Luxembourg station9:10 AMPrague hlavní nádraží82 S$1One-way6 changes
RE 5121 · 4114 · ICE 594 · IC 20451:33 PM16h37Luxembourg station6:10 AMPrague hlavní nádraží91 S$1One-way6 changes
Bus 82150 · 4122 · ICE 590 · 165016:10 PM15h00Luxembourg station9:10 AMPrague hlavní nádraží91 S$1One-way6 changes
RE 5123 · 4265 · ICE 1657 · S12:33 PM17h37Luxembourg station8:10 AMPrague hlavní nádraží96 S$1One-way5 changes
Bus 82116 · 4146 · ICE 692 · IC 24436:15 AM11h10Luxembourg station5:25 PMPrague hlavní nádraží338 S$1One-way5 changes
Bus 82110 · ICE 1091 · ICE 694 · IC 24454:00 AM11h15Luxembourg station3:15 PMPrague-Holešovice229 S$1One-way5 changes
Bus 82112 · 4144 · ICE 571 · 896854:45 AM11h36Luxembourg station4:21 PMPrague hlavní nádraží164 S$1One-way5 changes
5113 · 4106 · ICE 598 · IC 20499:33 AM11h52Luxembourg station9:25 PMPrague hlavní nádraží384 S$1One-way4 changes
Bus 82122 · ICE 1651 · S1 · 280129:15 AM11h55Luxembourg station9:10 PMPrague hlavní nádraží277 S$1One-way5 changes
Live departures
Luxembourg to Prague train times
The table below shows live departures for Luxembourg to Prague trains for today, Sunday, 27 September. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
Bus 82150 · 4122 · ICE 590 · 16501 | On time 6:10 PM Luxembourg station | 15h00 | 9:10 AM Prague hlavní nádraží | 6 changes | |
Bus 82158 · 4348 · EC 459 | On time 8:05 PM Luxembourg station | 13h20 | 9:25 AM Prague hlavní nádraží | 2 changes | |
Bus 82158 · 4348 · S3 · EC 459 | On time 8:05 PM Luxembourg station | 13h20 | 9:25 AM Prague hlavní nádraží | 3 changes | |
Bus 82158 · 4348 · EC 459 | On time 8:05 PM Luxembourg station | 13h20 | 9:25 AM Prague hlavní nádraží | 2 changes | |
| Monday, 28 September | |||||
Bus 82110 · ICE 1091 · ICE 694 · IC 2445 | On time 4:00 AM Luxembourg station | 11h15 | 3:15 PM Prague-Holešovice | 5 changes | |
Bus 82110 · ICE 1091+ 357 | On time 4:00 AM Luxembourg station | 12h21 | 4:21 PM Prague hlavní nádraží | 2 changes | |
Bus 82112 · ICE 932 · ICE 1557 · BUS 10383 | On time 4:45 AM Luxembourg station | 12h40 | 5:25 PM Prague hlavní nádraží | 4 changes | |
Bus 82112 · 4144 · ICE 571 · 89685 | On time 4:45 AM Luxembourg station | 11h36 | 4:21 PM Prague hlavní nádraží | 5 changes | |
Bus 82116 · 4146 · ICE 692 · IC 2443 | 6:15 AM Luxembourg station | 11h10 | 5:25 PM Prague hlavní nádraží | 5 changes | |
Bus 82116 · 4146 · ICE 513+ 359 | 6:15 AM Luxembourg station | 12h06 | 6:21 PM Prague hlavní nádraží | 3 changes | |
Bus 82122 · ICE 1651 · RJ 385+ TGV 9551 | On time 9:15 AM Luxembourg station | 12h10 | 9:25 PM Prague hlavní nádraží | 3 changes | |
Bus 82122 · ICE 1651 · S1 · 28012 | On time 9:15 AM Luxembourg station | 11h55 | 9:10 PM Prague hlavní nádraží | 5 changes | |
5113 · 4106 · ICE 598 · IC 2049 | On time 9:33 AM Luxembourg station | 11h52 | 9:25 PM Prague hlavní nádraží | 4 changes | |
5113 · 4106 · ICE 517+ 363 | 9:33 AM Luxembourg station | 12h49 | 10:22 PM Prague hlavní nádraží | 3 changes | |
5117 · 4110 · ICE 596 · IC 2047 | 11:33 AM Luxembourg station | 11h58 | 11:31 PM Prague hlavní nádraží | 4 changes | |
RE 5121 · 4114 · ICE 594 · IC 2045 | 1:33 PM Luxembourg station | 16h37 | 6:10 AM Prague hlavní nádraží | 6 changes | |
5121 · 4114 · ICE 594 · IC 2045 | 1:33 PM Luxembourg station | 16h37 | 6:10 AM Prague hlavní nádraží | 6 changes | |
RE 5123 · 4265 · ICE 1657 · S1 | 2:33 PM Luxembourg station | 17h37 | 8:10 AM Prague hlavní nádraží | 5 changes | |
Bus 82134 · 4116 · ICE 276 · ICE 1657 | On time 3:05 PM Luxembourg station | 17h05 | 8:10 AM Prague hlavní nádraží | 6 changes | |
Bus 82134 · 4116 · ICE 276 · ICE 1657 | On time 3:05 PM Luxembourg station | 17h05 | 8:10 AM Prague hlavní nádraží | 6 changes | |
Find all the dates and times for this journey
Compare prices and tickets Luxembourg to Prague by coach, train or flight
Compare coach, train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
28 Sept
29 Sept
30 Sept
01 Oct
02 Oct
03 Oct
04 Oct
05 Oct
06 Oct
07 Oct
08 Oct
09 Oct
10 Oct
11 Oct
12 Oct
13 Oct
14 Oct
15 Oct
16 Oct
17 Oct
18 Oct
Why should you book Luxembourg to Prague trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of České dráhy or alex-Länderbahn und Vogtlandbahn-GmbH to find the best option for your trip from Luxembourg to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Luxembourg to Prague.
Why book with Omio over Trainline, Wanderu or Raileurope?
- Compare with other providers: On Omio, you can also compare tickets for the likes of České dráhy or alex-Länderbahn und Vogtlandbahn-GmbH to find the best option for your trip from Luxembourg to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Luxembourg to Prague.
Journey information
Overview: Train from Luxembourg to Prague
Trains from Luxembourg to Prague run on average 8 times per day, taking around 11h 16m. Cheap train tickets for this journey start at 73S$ but you can travel from only 26S$ by flight.
The earliest train runs at 00:30, the last at 23:54. The fastest train covers the 596 km distance in 9h 46m.
Distance 596 km |
Average train duration 11h 16m |
Cheapest ticket price 73S$ |
Trains per day 8 |
Fastest train 9h 46m |
First train 12:30 AM |
Last train 11:54 PM |
Cheapest Month Dec |
Cheapest Day Mon |
High Season Jul - Sept |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Mon |
Best time to book 42 days |
Train companies: Deutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH from Luxembourg to Prague trainsDeutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH trains will get you between Luxembourg and Prague from 26S$. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
alex-Länderbahn und Vogtlandbahn-GmbH
České dráhy
FAQs: Luxembourg to Prague train
Find answers to the most common questions about traveling from Luxembourg to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Luxembourg and Prague
Most Luxembourg to Prague trains use the Luxembourg to Praha hlavní nádraží station pair, with some services arriving at Praha-Holesovice. Use this guide to compare Luxembourg and Prague train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Which Luxembourg station do trains to Prague leave from?
Getting to Luxembourg from Luxembourg city centre
Luxembourg is 1 km from Luxembourg city centre. Public transport options include:
Luxembourg train station facilities and services
Luxembourg has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk and Luggage Carts.
Food and drink
Food options include: Brasserie Schuman, Vapiano Luxembourg Gare
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Luxembourg. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Luxembourg. Lost and found is available at the station.
Parking, taxis and toilets
Available at Luxembourg: Parking, Taxis, WC.
Bike and car services
Available at Luxembourg: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Luxembourg: Elevators, ramps, restrooms.
Shops, hotels and contact
Nearby hotels include Hotel Empire, Hotel Carlton, Park Inn by Radisson Luxembourg City.
Getting to Luxemburg, Rue de la Déportation (Gare de Hollerich) from Luxembourg city centre
Luxemburg, Rue de la Déportation (Gare de Hollerich) is 1 km from Luxembourg city centre. Check local transport options before travel.
Getting to Luxembourg, Gare Centrale (quai 13) from Luxembourg city centre
Luxembourg, Gare Centrale (quai 13) is 1 km from Luxembourg city centre. Public transport options include:
Luxembourg, Gare Centrale (quai 13) train station facilities and services
Luxembourg, Gare Centrale (quai 13) has practical services for this route, including Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Bike Parking, Bike Rental and Car Rental.
Food and drink
Food and drink options are available at Luxembourg, Gare Centrale (quai 13).
Wi-Fi and ATMs
ATMs are available at Luxembourg, Gare Centrale (quai 13).
Parking, taxis and toilets
Available at Luxembourg, Gare Centrale (quai 13): Parking, Taxis, WC.
Bike and car services
Available at Luxembourg, Gare Centrale (quai 13): Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Luxembourg, Gare Centrale (quai 13).
Which Prague station do trains from Luxembourg arrive at?
Getting to Praha hlavní nádraží from Prague city centre
Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:
Praha hlavní nádraží train station facilities and services
Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk and Luggage Carts.
Food and drink
Food options include: Restaurant Fantova Kavárna, Sushi Time
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.
Parking, taxis and toilets
Available at Praha hlavní nádraží: Parking, Taxis, WC.
Bike and car services
Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.
Getting to Praha-Holesovice from Prague city centre
Praha-Holesovice is 2 km from Prague city centre. Public transport options include:
Praha-Holesovice train station facilities and services
Praha-Holesovice has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk and Luggage Carts.
Food and drink
Food options include: Restaurant Na Kovárně, Cross Club
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Praha-Holesovice. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Praha-Holesovice. Lost and found is available at the station.
Parking, taxis and toilets
Available at Praha-Holesovice: Parking, Taxis, WC.
Bike and car services
Available at Praha-Holesovice: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Praha-Holesovice: Ramps, restrooms.
Shops, hotels and contact
Nearby hotels include Mama Shelter Prague, Plaza Alta Hotel, Hotel Belvedere.
Getting to Praha Masarykovo Nádraží from Prague city centre
Praha Masarykovo Nádraží train station facilities and services
Praha Masarykovo Nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk and Luggage Carts.
Food and drink
Food options include: Restaurant Kotleta, Café Imperial
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Praha Masarykovo Nádraží. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Praha Masarykovo Nádraží. Lost and found is available at the station.
Parking, taxis and toilets
Available at Praha Masarykovo Nádraží: Parking, Taxis, WC.
Bike and car services
Available at Praha Masarykovo Nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Praha Masarykovo Nádraží: Ramps.
Shops, hotels and contact
Nearby hotels include Hotel Kings Court, Grand Hotel Bohemia, Hotel Paris Prague.
Most popular train connections from Luxembourg
More options for your journey from Luxembourg to Prague
Here are some other resources that might have the information you need


