Luxembourg to Prague train with Deutsche Bahn (ICE,RE,EC,IC)

Mon, 28 Sept
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Deutsche Bahn
České dráhy
alex-Länderbahn und Vogtlandbahn-GmbH
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Deutsche Bahn
České dráhy
alex-Länderbahn und Vogtlandbahn-GmbH
SNCF | TGV INOUI
Italo
2,000+ travel companies
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The cheapest and fastest trains from Luxembourg to Prague

Showing times, prices and bookable tickets for 28 Sept

Cheapest price on 28 Sept

79S$

Average ticket price on 28 Sept

208S$

Fastest journey on 28 Sept

11 h 10 m

Average journey duration on 28 Sept

11 h 34 m

Trains on 28 Sept

19

Distance

596 km

Cheap tickets

The best way to find a cheap train ticket from Luxembourg to Prague is to book your journey as far in advance as possible and to avoid travelling at rush hour.

The average ticket from Luxembourg to Prague will cost around 208S$ if you buy it on the day, but you can find cheap train tickets today for only 79S$.

Fast trains

To travel from Luxembourg to Prague you need to make at least 4 changes.

  • Deutsche BahnBus 82158 · 4132 · EC 459
    8:05 PM13h20
    Luxembourg station
    9:25 AMPrague hlavní nádraží
    79 S$1One-way
    2 changes
  • Deutsche BahnBus 82150 · 4122 · ICE 590 · 16501
    6:10 PM15h00
    Luxembourg station
    9:10 AMPrague hlavní nádraží
    82 S$1One-way
    6 changes
  • Deutsche BahnRE 5121 · 4114 · ICE 594 · IC 2045
    1:33 PM16h37
    Luxembourg station
    6:10 AMPrague hlavní nádraží
    91 S$1One-way
    6 changes
  • Deutsche BahnBus 82150 · 4122 · ICE 590 · 16501
    6:10 PM15h00
    Luxembourg station
    9:10 AMPrague hlavní nádraží
    91 S$1One-way
    6 changes
  • Deutsche BahnRE 5123 · 4265 · ICE 1657 · S1
    2:33 PM17h37
    Luxembourg station
    8:10 AMPrague hlavní nádraží
    96 S$1One-way
    5 changes

Live departures

Luxembourg to Prague train times

The table below shows live departures for Luxembourg to Prague trains for today, Sunday, 27 September. You can also manually refresh the results below to see updated train journeys.

Last updated at
ProviderDepartsDurationArrivesChanges
Tickets
Deutsche BahnBus 82150 · 4122 · ICE 590 · 16501
On time
6:10 PM Luxembourg station
15h00
9:10 AM Prague hlavní nádraží
6 changes
Deutsche BahnBus 82158 · 4348 · EC 459
On time
8:05 PM Luxembourg station
13h20
9:25 AM Prague hlavní nádraží
2 changes
Deutsche BahnBus 82158 · 4348 · S3 · EC 459
On time
8:05 PM Luxembourg station
13h20
9:25 AM Prague hlavní nádraží
3 changes
Deutsche BahnBus 82158 · 4348 · EC 459
On time
8:05 PM Luxembourg station
13h20
9:25 AM Prague hlavní nádraží
2 changes
Monday, 28 September
Deutsche BahnBus 82110 · ICE 1091 · ICE 694 · IC 2445
On time
4:00 AM Luxembourg station
11h15
3:15 PM Prague-Holešovice
5 changes
Deutsche BahnBus 82110 · ICE 1091+alex-Länderbahn und Vogtlandbahn-GmbH357
On time
4:00 AM Luxembourg station
12h21
4:21 PM Prague hlavní nádraží
2 changes
Deutsche BahnBus 82112 · ICE 932 · ICE 1557 · BUS 10383
On time
4:45 AM Luxembourg station
12h40
5:25 PM Prague hlavní nádraží
4 changes
Deutsche BahnBus 82112 · 4144 · ICE 571 · 89685
On time
4:45 AM Luxembourg station
11h36
4:21 PM Prague hlavní nádraží
5 changes
Deutsche BahnBus 82116 · 4146 · ICE 692 · IC 24436:15 AM Luxembourg station
11h10
5:25 PM Prague hlavní nádraží5 changes
Deutsche BahnBus 82116 · 4146 · ICE 513+alex-Länderbahn und Vogtlandbahn-GmbH3596:15 AM Luxembourg station
12h06
6:21 PM Prague hlavní nádraží3 changes
Deutsche BahnBus 82122 · ICE 1651 · RJ 385+TGVTGV 9551
On time
9:15 AM Luxembourg station
12h10
9:25 PM Prague hlavní nádraží
3 changes
Deutsche BahnBus 82122 · ICE 1651 · S1 · 28012
On time
9:15 AM Luxembourg station
11h55
9:10 PM Prague hlavní nádraží
5 changes
Deutsche Bahn5113 · 4106 · ICE 598 · IC 2049
On time
9:33 AM Luxembourg station
11h52
9:25 PM Prague hlavní nádraží
4 changes
Deutsche Bahn5113 · 4106 · ICE 517+alex-Länderbahn und Vogtlandbahn-GmbH3639:33 AM Luxembourg station
12h49
10:22 PM Prague hlavní nádraží3 changes
Deutsche Bahn5117 · 4110 · ICE 596 · IC 204711:33 AM Luxembourg station
11h58
11:31 PM Prague hlavní nádraží4 changes
Deutsche BahnRE 5121 · 4114 · ICE 594 · IC 20451:33 PM Luxembourg station
16h37
6:10 AM Prague hlavní nádraží6 changes
Deutsche Bahn5121 · 4114 · ICE 594 · IC 20451:33 PM Luxembourg station
16h37
6:10 AM Prague hlavní nádraží6 changes
Deutsche BahnRE 5123 · 4265 · ICE 1657 · S12:33 PM Luxembourg station
17h37
8:10 AM Prague hlavní nádraží5 changes
Deutsche BahnBus 82134 · 4116 · ICE 276 · ICE 1657
On time
3:05 PM Luxembourg station
17h05
8:10 AM Prague hlavní nádraží
6 changes
Deutsche BahnBus 82134 · 4116 · ICE 276 · ICE 1657
On time
3:05 PM Luxembourg station
17h05
8:10 AM Prague hlavní nádraží
6 changes

Find all the dates and times for this journey

Compare prices and tickets Luxembourg to Prague by coach, train or flight

Compare coach, train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Luxembourg to Prague trains with Omio?

Deutsche Bahn as well as České dráhy or alex-Länderbahn und Vogtlandbahn-GmbH offer trains services from Luxembourg to Prague.
Omio is an official ticket reseller for all your travel options from Luxembourg to Prague.

Why book with Omio vs Deutsche Bahn?

  • Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of České dráhy or alex-Länderbahn und Vogtlandbahn-GmbH to find the best option for your trip from Luxembourg to Prague.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Luxembourg to Prague.

Why book with Omio over Trainline, Wanderu or Raileurope?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of České dráhy or alex-Länderbahn und Vogtlandbahn-GmbH to find the best option for your trip from Luxembourg to Prague.
  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Luxembourg to Prague.

Journey information

Overview: Train from Luxembourg to Prague

LuxembourgLuxembourg
CzechiaCzechia
Icon of train

Trains from Luxembourg to Prague run on average 8 times per day, taking around 11h 16m. Cheap train tickets for this journey start at 73S$ but you can travel from only 26S$ by flight.

The earliest train runs at 00:30, the last at 23:54. The fastest train covers the 596 km distance in 9h 46m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from 26S$
Distance
596 km
Average train duration
11h 16m
Cheapest ticket price
73S$
Trains per day
8
Fastest train
9h 46m
First train
12:30 AM
Last train
11:54 PM
Cheapest Month
Dec
Cheapest Day
Mon
High Season
Jul - Sept
Low Season
Jan - Mar
Busiest Day
Wed
Least Busy Day
Mon
Best time to book
42 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from 26S$

Train companies: Deutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH from Luxembourg to Prague trainsDeutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH trains will get you between Luxembourg and Prague from 26S$. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Deutsche Bahn

About
Deutsche Bahn (DB) is Germany’s main train operator, running around 40,000 domestic and international services each day. Its fleet includes a variety of train types: high-speed ICE (Intercity Express) trains, reaching up to 300 km/h; IC (Intercity) and EC (EuroCity) trains for long-distance travel; and IRE (Interregio-Express), RE (Regional Express), and RB (Regionalbahn) services for regional and local connections. While bathrooms are standard on all trains, amenities such as onboard restaurants and free Wi-Fi are available only on certain train types and routes. DB offers a wide range of fares, including Super Saver, Saver, and Flexible tickets, along with discount cards like the BahnCard 25, 50, and 100. Additional options include single tickets, day tickets, and group tickets. Popular routes include Berlin–Munich, Hamburg–Frankfurt, Cologne–Stuttgart, Berlin–Dresden, and Hamburg–Cologne, as well as numerous regional services across Germany.
Luggage & cancellation policy
Average Deutsche Bahn Duration
9h 46m
Cheapest Deutsche Bahn Price
73S$
Deutsche Bahn frequency
4 a day
Luggage included
Passengers are allowed to bring hand luggage and one additional larger item free of charge, provided they can carry it themselves
Luggage storage
Luggage can be stored in overhead racks, under the seat, or in designated luggage areas near the doors or in the middle of the carriage.
Cancellation Policy
Tickets can be canceled based on their fare conditions as mentioned in what type of train tickets are refundable?
Refund
If DB cancels a train, passengers are entitled to a full refund of the ticket price.
Amenities on board the train
Wifi
Food sold onboard
Most ICE and many IC/EC trains have:
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Seat reservation
Second Class:
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Toilets
USB plugs
Accessibility
DB trains are equipped with facilities for passengers with reduced mobility, including wheelchair spaces, accessible restrooms, and assistance services.
Pets
Small pets (e.g. cats, small dogs, etc.):
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Quiet zone

alex-Länderbahn und Vogtlandbahn-GmbH

About
agilis is a railway company operating regional trains based in Regensburg in Bavaria since 2010. It operates in the German state of Bavaria connecting cities like Ulm, Ingolstadt, Regensburg and Plattling. They offer single tickets and comfortable trains with some popular routes covering Ulm to Regensburg, Neumarkt to Passau and Ingolstadt to Plattling.
Luggage & cancellation policy
Average alex-Länderbahn und Vogtlandbahn-GmbH Duration
10h 0m
Cheapest alex-Länderbahn und Vogtlandbahn-GmbH Price
73S$
alex-Länderbahn und Vogtlandbahn-GmbH frequency
1 a day
Luggage included
One piece of hand luggage and one larger piece included
Luggage storage
Overhead racks and designated luggage areas
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund for canceled services
Amenities on board the train
Wifi
Food sold onboard
Snack and beverage service available on some routes
Seat reservation
Seat reservations available for additional fee
Toilets
USB plugs
Accessibility
Wheelchair spaces available, assistance for boarding/alighting
Pets
Small pets in carriers travel free, larger dogs require ticket and muzzle
Quiet zone

České dráhy

About
Czech Railways (České dráhy, ČD) is the largest railway company in the Czech Republic, connecting major cities, small towns, and even international destinations across Europe. Its extensive fleet of modern trains ranges from comfortable regional services with A/C and onboard WiFi to high-speed trains offering dining cars, power outlets, and premium seating for long-distance journeys. Czech Railways combines affordability and convenience, making it a popular choice for travelers exploring the Czech Republic and beyond.
Luggage & cancellation policy
Average České dráhy Duration
10h 27m
Cheapest České dráhy Price
97S$
České dráhy frequency
5 a day

FAQs: Luxembourg to Prague train

Find answers to the most common questions about traveling from Luxembourg to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

FAQs
Cheap train tickets from Luxembourg to Prague can start from as little as 73S$ when you book in advance. The average train ticket price for Luxembourg to Prague is 255S$; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by train from Luxembourg to Prague is 9h 46m to travel the 596 km long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest train from Luxembourg to Prague leaves at 12:30 am. Plan your trip with the Journey Planner from Omio.
The latest train from Luxembourg to Prague leaves at 11:54 pm.
There are 8 trains a day from Luxembourg to Prague which require at least one change with Deutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH. Schedules can vary on holidays or weekends with fewer trains.
When taking a train from Luxembourg to Prague, you can count on Deutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH for the best way to get you to Prague. You can also check all possible train companies who offer a service between Luxembourg and Prague and compare the amenities they offer before buying a train ticket.
A trip to Prague from Luxembourg is worth doing but not as a day trip with a journey time of 9h 46m each way. Check with Omio app the best way to travel.
It's helpful to compare your options as there are 3 ways to travel between Luxembourg and Prague including taking a coach, train and flight.

popular train stations

Important Stations and Airports in Luxembourg and Prague

Most Luxembourg to Prague trains use the Luxembourg to Praha hlavní nádraží station pair, with some services arriving at Praha-Holesovice. Use this guide to compare Luxembourg and Prague train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.

Departure train stations in Luxembourg
Arrival train stations in Prague

Which Luxembourg station do trains to Prague leave from?

Trains from Luxembourg to Prague leave from Luxembourg. The station is 1 km from Luxembourg city centre at 11 Place de la Gare, 1616 Luxembourg, Luxembourg.
Luxembourg11 Place de la Gare, 1616 Luxembourg, Luxembourg+352 2489 2489WifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation DeskLuggage Carts
City-centre transport

Getting to Luxembourg from Luxembourg city centre

Luxembourg is 1 km from Luxembourg city centre. Public transport options include:

TrainRe, Rb · 4m · 2S$ · every ~8 min
BusCn3, Cn2, Cn1, 4, 22, 18, 14, 13, 10 · 5m · every ~43 min
TramT1 · 5m · every ~26 min

Luxembourg train station facilities and services

Luxembourg has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk and Luggage Carts.

Food and drink

Food options include: Brasserie Schuman, Vapiano Luxembourg Gare

Wi-Fi and ATMs

Free. ATMs are available in the train station.

Tickets and information

Ticket office support is available at Luxembourg. Information desks are located in the main hall.

Luggage and lost property

Luggage storage is available at Luxembourg. Lost and found is available at the station.

Parking, taxis and toilets

Available at Luxembourg: Parking, Taxis, WC.

Bike and car services

Available at Luxembourg: Bike Parking, Bike Rental, Car Rental.

Accessibility

Accessibility facilities are available at Luxembourg: Elevators, ramps, restrooms.

Shops, hotels and contact

Nearby hotels include Hotel Empire, Hotel Carlton, Park Inn by Radisson Luxembourg City.

Luxemburg, Rue de la Déportation (Gare de Hollerich)Gasperich, 1415 Luxembourg
City-centre transport

Getting to Luxemburg, Rue de la Déportation (Gare de Hollerich) from Luxembourg city centre

Luxemburg, Rue de la Déportation (Gare de Hollerich) is 1 km from Luxembourg city centre. Check local transport options before travel.

Luxembourg, Gare Centrale (quai 13)11 Pl. de la Gare, 1490 Luxembourg+352 24 89 24 89ParkingDiningATMTaxisAccessibilityWCHotelBike ParkingBike RentalCar Rental
City-centre transport

Getting to Luxembourg, Gare Centrale (quai 13) from Luxembourg city centre

Luxembourg, Gare Centrale (quai 13) is 1 km from Luxembourg city centre. Public transport options include:

TrainRe, Rb · 4m · 2S$ · every ~8 min
BusCn8, 33, Cn3, Cn2, Cn1, 9, 4, 3, 2, 18, 14, 10 · 5m · every ~52 min
TramT1 · 3m · every ~26 min

Luxembourg, Gare Centrale (quai 13) train station facilities and services

Luxembourg, Gare Centrale (quai 13) has practical services for this route, including Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Bike Parking, Bike Rental and Car Rental.

Food and drink

Food and drink options are available at Luxembourg, Gare Centrale (quai 13).

Wi-Fi and ATMs

ATMs are available at Luxembourg, Gare Centrale (quai 13).

Parking, taxis and toilets

Available at Luxembourg, Gare Centrale (quai 13): Parking, Taxis, WC.

Bike and car services

Available at Luxembourg, Gare Centrale (quai 13): Bike Parking, Bike Rental, Car Rental.

Accessibility

Accessibility facilities are available at Luxembourg, Gare Centrale (quai 13).

Most popular train connections from Luxembourg

More options for your journey from Luxembourg to Prague

Here are some other resources that might have the information you need

HomeTrainsTrains in CzechiaLuxembourg to Prague train

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