The cheapest and fastest flights from Santiago to Antofagasta
- Cheapest price on 13 Nov
- $41
- Average ticket price on 13 Nov
- $76
- Fastest journey on 13 Nov
- 2 h
- Average journey duration on 13 Nov
- 2 h 1 m
- Flights on 13 Nov
- 7
- Distance
- 1091 km
The best way to find a cheap flight ticket from Santiago to Antofagasta is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Santiago to Antofagasta will cost around $76 if you buy it on the day, but you can find cheap flight tickets today for only $41.
On Fri, 13 Nov, we found 7 flights from Santiago to Antofagasta, including 7 direct services.
These direct flights cover the 1091 km distance in an average of 2 h 1 m but if you time it right, some flights will get you there in just 2 h .
The slowest flights will take 2 h 1 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

1:54 PM 2h05 Santiago 3:59 PM Antofagasta $41 1 One-way 0 changes
7:49 AM 2h01 Santiago 9:50 AM Antofagasta $52 1 One-way 0 changes
6:45 PM 2h01 Santiago 8:46 PM Antofagasta $63 1 One-way 0 changes
9:44 AM 2h01 Santiago 11:45 AM Antofagasta $64 1 One-way 0 changes
7:21 PM 2h00 Santiago 9:21 PM Antofagasta $71 1 One-way 0 changes

7:21 PM 2h00 Santiago 9:21 PM Antofagasta $71 1 One-way 0 changes
7:49 AM 2h01 Santiago 9:50 AM Antofagasta $52 1 One-way 0 changes
12:07 AM 2h01 Santiago 2:08 AM Antofagasta $162 1 One-way 0 changes
9:44 AM 2h01 Santiago 11:45 AM Antofagasta $64 1 One-way 0 changes
6:45 PM 2h01 Santiago 8:46 PM Antofagasta $63 1 One-way 0 changes
Journey information
Overview: Santiago to Antofagasta flight
Flights from Santiago to Antofagasta depart on average 23 times per day, taking around 3h 4m. Cheap flight tickets for this journey start at $26 if you book in advance.
There are 15 flights per day. The earliest flight runs at 00:09, the last at 23:58. The fastest flight covers the 1091 km distance in 1h 58m. October is the cheapest month to fly.
Distance 1091 km |
Average flight duration 3h 4m |
Cheapest ticket price $26 |
Flights per day 23 |
Direct flights 15 |
Fastest flight 1h 58m |
First flight 12:09 AM |
Last flight 11:58 PM |
Cheapest Month Oct |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Jul - Sept |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 21 days |
Frequently asked questions about your Santiago to Antofagasta trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Santiago to Antofagasta.
Live departures
Santiago to Antofagasta flight times
The table below shows live departures for Santiago to Antofagasta flights for today, Thursday, 12 November. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
![]() | 8:57 AM Santiago | 2h05 | 11:02 AM Antofagasta | 0 changesdirect | |
![]() | 1:06 PM Santiago | 2h00 | 3:06 PM Antofagasta | 0 changesdirect | |
![]() | 2:22 PM Santiago | 2h01 | 4:23 PM Antofagasta | 0 changesdirect | |
![]() | 6:14 PM Santiago | 2h01 | 8:15 PM Antofagasta | 0 changesdirect | |
![]() | 9:20 PM Santiago | 2h00 | 11:20 PM Antofagasta | 0 changesdirect | |
![]() | 10:04 PM Santiago | 2h01 | 12:05 AM Antofagasta | 0 changesdirect | |
| Friday, 13 November | |||||
![]() | 12:07 AM Santiago | 2h01 | 2:08 AM Antofagasta | 0 changesdirect | |
![]() | 7:49 AM Santiago | 2h01 | 9:50 AM Antofagasta | 0 changesdirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Why should you book Santiago to Antofagasta flights with Omio?
Why book with Omio vs jetsmart?
- Compare with other providers: On Omio, you can not only buy tickets for jetsmart, but also compare tickets for the likes of Latam Airlines, Sky Airline or CitizenPlane to find the best option for your trip from Santiago to Antofagasta.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare jetsmart with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Santiago to Antofagasta.
Why book with Omio over Edreams, Kayak or Skyscanner?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Latam Airlines, Sky Airline or CitizenPlane to find the best option for your trip from Santiago to Antofagasta.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Santiago to Antofagasta.
Airlines: Latam Airlines, Sky Airline, jetsmart, CitizenPlane from Santiago to AntofagastaFind the best flights between Santiago to Antofagasta with Omio's travel partners Latam Airlines, Sky Airline, jetsmart, CitizenPlane from $26. We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Latam Airlines
Sky Airline
jetsmart
CitizenPlane
Companies, tickets, and onboard amenities between Santiago and Antofagasta
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
FAQs: Santiago to Antofagasta flights
Find answers to the most common questions about traveling from Santiago to Antofagasta by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Antofagasta, this guide helps you travel smarter and with confidence.

popular airports
Important Stations and Airports in Santiago and Antofagasta
Most Santiago to Antofagasta flights use the Santiago to Antofagasta airport pair. Use this guide to compare Santiago and Antofagasta airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Which Santiago airport do flights to Antofagasta leave from?
Getting to Santiago from Santiago city centre
Santiago is 8 km from Santiago city centre. Public transport options include:
Santiago airport facilities and services
Santiago has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office and Car Rental.
Food and drink
Food options include: Restaurants available in both domestic and intertiol terminals; options include fast food and Chilean cuisine.
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are located in both domestic and intertiol terminals.
Luggage and lost property
Lost and found is available at the station.
Parking, taxis and toilets
Available at Santiago: Parking, Taxis, WC.
Bike and car services
Available at Santiago: Car Rental.
Accessibility
Accessibility facilities are available at Santiago: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Hotels nearby include Holiday Inn Santiago Airport, within walking distance..
Which Antofagasta airport do flights from Santiago arrive at?
Getting to Antofagasta from Antofagasta city centre
Antofagasta is 23 km from Antofagasta city centre. Public transport options include:
Antofagasta airport facilities and services
Antofagasta has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Lounge, Lost and Found Office and Car Rental.
Food and drink
Food options include: Several restaurants and cafes are located in the main terminal, offering local and intertiol cuisine.
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are located in the arrivals and departures areas.
Luggage and lost property
Lost and found is available at the station.
Parking, taxis and toilets
Available at Antofagasta: Parking, Taxis, WC.
Bike and car services
Available at Antofagasta: Car Rental.
Accessibility
Accessibility facilities are available at Antofagasta: Elevators, ramps.
