The cheapest and fastest coaches from Rome to Prague
Cheapest price
128€
Average price
176€
Fastest journey
19 h 55 m
Average duration
20 h 15 m
Buses per day
43
Distance
923 km
The best way to find a cheap coach ticket from Rome to Prague is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Rome to Prague will cost around 176€ if you buy it on the day, but you can find cheap coach tickets today for only 128€.
Of the 43 buses that leave Rome for Prague every day 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct buses cover the 923 km distance in an average of 20 h 15 m but if you time it right, some buses will get you there in just 19 h 55 m .
The slowest buses will take 20 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus5:05 PM20h50Roma, Autostazione Tiburtina1:55 PMPraha, ÚAN Florenc128 €1One-way0 changes
FlixBus5:05 PM20h40Roma, Autostazione Tiburtina1:45 PMPrague, Central Train Station128 €1One-way0 changes
FlixBus · FlixBus9:00 PM20h30Roma, Autostazione Tiburtina5:30 PMPrague, Central Train Station145 €1One-way1 change
FlixBus · FlixBus9:00 PM20h45Roma, Autostazione Tiburtina5:45 PMPraha, ÚAN Florenc145 €1One-way1 change
FlixBus · FlixBus · FlixBus5:05 PM24h30Roma, Autostazione Tiburtina5:35 PMPraha, M. Horákové (Hradčanská)145 €1One-way2 changes
FlixBus · FlixBus · FlixBus5:25 PM19h55Roma, Autostazione (Metro Anagnina)1:20 PMPrague, Central Train Station154 €1One-way2 changes
FlixBus · FlixBus · FlixBus5:25 PM20h05Roma, Autostazione (Metro Anagnina)1:30 PMPraha, ÚAN Florenc154 €1One-way2 changes
FlixBus · FlixBus1:05 PM20h20Roma, Autostazione (Metro Anagnina)9:25 AMPraha, ÚAN Florenc177 €1One-way1 change
FlixBus · FlixBus10:55 PM20h25Roma, Autostazione Tiburtina7:20 PMPrague, Central Train Station195 €1One-way1 change
FlixBus · FlixBus9:00 PM20h30Roma, Autostazione Tiburtina5:30 PMPrague, Central Train Station145 €1One-way1 change
Travel Information
Compare train, coach and flight for Rome to Prague
Omio recommends booking the flight as it is the most popular option from Rome to Prague among Omio's users. If you are prioritising price take the coach with prices starting from 56€. For those with little time consider booking a flight which can get you there in 2h 50m. In case you are seeking to minimise your carbon footprint the coach is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a coach costs an average of 56€, and a train costs an average of 236€.
Distance: 923 km
Compare bus with
| Coach | Most popular Flight | Train |
|---|---|---|
91€ Average Price Cheapest | 122€ Average Price | 239€ Average Price |
20h 23m Average total duration 19h 53m Onboard + 30m Additional time* | 5h 50m Average total duration Fastest 2h 50m Onboard + 3h 0m Additional time* | 18h 2m Average total duration 17h 32m Onboard + 30m Additional time* |
0.9 - 2.3kg CO2 emissions Lowest | 2.8 - 5.5kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Rome to Prague bus times
The table below shows live departures for Rome to Prague coaches for today, Friday, 14 August. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 21h30 | 7:00 AM Prague, Central Train Station | 1 change | |
FlixBus · FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 23h25 | 8:55 AM Praha, Na Knížecí | 2 changes | |
FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 21h40 | 7:10 AM Praha, ÚAN Florenc | 1 change | |
FlixBus · FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 22h00 | 7:30 AM Praha, M. Horákové (Hradčanská) | 2 changes | |
FlixBus · FlixBus · FlixBus | 10:10 AM Roma, Autostazione Tiburtina | 25h20 | 11:30 AM Praha, Zličín | 2 changes | |
FlixBus · FlixBus · FlixBus | 11:40 AM Roma, Autostazione Tiburtina | 22h55 | 10:35 AM Prague, Central Train Station | 2 changes | |
FlixBus · FlixBus · FlixBus | 12:00 PM Roma, Autostazione (Metro Anagnina) | 23h45 | 11:45 AM Praha, Na Knížecí | 2 changes | |
FlixBus · FlixBus · FlixBus | 12:10 PM Roma, Autostazione Tiburtina | 24h00 | 12:10 PM Prague, Central Train Station | 2 changes | |
FlixBus · FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 25h25 | 1:45 PM Praha, Černý Most | 2 changes | |
FlixBus · FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 23h25 | 11:45 AM Praha, Na Knížecí | 2 changes | |
FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 21h05 | 9:25 AM Praha, ÚAN Florenc | 1 change | |
FlixBus · FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 25h00 | 1:20 PM Praha, Roztyly | 2 changes | |
FlixBus · FlixBus · FlixBus | 12:45 PM Roma, Autostazione (Metro Anagnina) | 25h00 | 1:45 PM Praha, Černý Most | 2 changes | |
FlixBus · FlixBus · FlixBus | 12:45 PM Roma, Autostazione (Metro Anagnina) | 24h35 | 1:20 PM Praha, Roztyly | 2 changes | |
FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 24h25 | 1:30 PM Praha, Roztyly | 2 changes | |
FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 21h30 | 10:35 AM Prague, Central Train Station | 2 changes | |
FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 20h20 | 9:25 AM Praha, ÚAN Florenc | 1 change | |
FlixBus · FlixBus | 5:00 PM Roma, Autostazione Tiburtina | 27h00 | 8:00 PM Prague, Central Train Station | 1 change | |
FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 20h40 | 1:45 PM Prague, Central Train Station | 0 changesdirect | |
FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 20h50 | 1:55 PM Praha, ÚAN Florenc | 0 changesdirect | |
FlixBus · FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 23h25 | 4:30 PM Praha, Roztyly | 2 changes | |
FlixBus · FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 25h25 | 6:30 PM Praha, Zličín | 2 changes | |
FlixBus · FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 24h30 | 5:35 PM Praha, M. Horákové (Hradčanská) | 2 changes | |
FlixBus · FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 23h05 | 4:10 PM Praha, Černý Most | 2 changes | |
FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 19h55 | 1:20 PM Prague, Central Train Station | 2 changes | |
FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 22h45 | 4:10 PM Praha, Černý Most | 2 changes | |
FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 25h45 | 7:10 PM Praha, Na Knížecí | 2 changes | |
FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 24h10 | 5:35 PM Praha, M. Horákové (Hradčanská) | 2 changes | |
FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 20h05 | 1:30 PM Praha, ÚAN Florenc | 2 changes | |
FlixBus · FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 22h10 | 7:10 PM Praha, Na Knížecí | 2 changes | |
FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 20h30 | 5:30 PM Prague, Central Train Station | 1 change | |
FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 20h45 | 5:45 PM Praha, ÚAN Florenc | 1 change | |
FlixBus · FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 26h55 | 11:55 PM Prague, Central Train Station | 2 changes | |
FlixBus · FlixBus | 10:55 PM Roma, Autostazione Tiburtina | 20h25 | 7:20 PM Prague, Central Train Station | 1 change | |
FlixBus · FlixBus | 10:55 PM Roma, Autostazione Tiburtina | 20h35 | 7:30 PM Praha, ÚAN Florenc | 1 change | |
FlixBus · FlixBus · FlixBus | 10:55 PM Roma, Autostazione Tiburtina | 24h00 | 10:55 PM Praha, Na Knížecí | 2 changes | |
FlixBus · FlixBus · FlixBus | 11:05 PM Roma, Autostazione Tiburtina | 23h30 | 10:35 PM Praha, Roztyly | 2 changes | |
FlixBus · FlixBus | 11:05 PM Roma, Autostazione Tiburtina | 21h50 | 8:55 PM Praha, ÚAN Florenc | 1 change | |
FlixBus · FlixBus | 11:05 PM Roma, Autostazione Tiburtina | 22h25 | 9:30 PM Praha, Černý Most | 1 change | |
FlixBus · FlixBus · FlixBus | 11:05 PM Roma, Autostazione Tiburtina | 27h20 | 2:25 AM Prague, Central Train Station | 2 changes | |
FlixBus · FlixBus · FlixBus | 11:50 PM Roma, Autostazione Tiburtina | 27h25 | 3:15 AM Prague, Central Train Station | 2 changes | |
| Saturday, 15 August | |||||
FlixBus · FlixBus | 7:30 AM Roma, Autostazione Tiburtina | 22h15 | 5:45 AM Praha, ÚAN Florenc | 1 change | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Prague by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
14 Aug
15 Aug
16 Aug
17 Aug
18 Aug
19 Aug
20 Aug
21 Aug
22 Aug
23 Aug
24 Aug
25 Aug
26 Aug
27 Aug
28 Aug
29 Aug
30 Aug
31 Aug
01 Sept
02 Sept
03 Sept
Why should you book Rome to Prague coaches with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome to Prague.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rome to Prague.
Journey information
Overview: Bus from Rome to Prague
Buses from Rome to Prague run on average 38 times per day, taking around 19h 53m. Cheap bus tickets for this journey start at 56€ but you can travel from only 15€ by flight.
There are 2 coaches per day. The earliest coach runs at 00:10, the last at 23:55. The fastest coach covers the 923 km distance in 20h 10m.
Distance 923 km |
Average bus duration 19h 53m |
Cheapest ticket price 56€ |
Buses per day 38 |
Direct buses 2 |
Fastest bus 20h 10m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 28 days |
Bus providers: FlixBus from Rome to PragueYou can travel by bus between Rome to Prague with FlixBus for as low as 15€. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Rome to Prague coach
Find answers to the most common questions about traveling from Rome to Prague by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Important Stations and Airports in Rome and Prague
Most Rome to Prague buses use the Roma, Autostazione Tiburtina to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Rome and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Rome station do buses to Prague leave from?
Getting to Roma, Autostazione Tiburtina from Rome city centre
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina bus station facilities and services
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Food and drink
Food options include: Cafes and vending machines available.
Wi-Fi and ATMs
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Tickets and information
Ticket office support is available at Roma, Autostazione Tiburtina.
Parking, taxis and toilets
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Getting to Roma, Autostazione (Metro Anagnina) from Rome city centre
Getting to Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine" from Rome city centre
Which Prague station do buses from Rome arrive at?
Getting to Praha, Hlavní Nádraží from Prague city centre
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží bus station facilities and services
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food and drink
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Tickets and information
Ticket office support is available at Praha, Hlavní Nádraží.
Parking, taxis and toilets
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Getting to Praha, ÚAN Florenc from Prague city centre
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc bus station facilities and services
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food and drink
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Tickets and information
Ticket office support is available at Praha, ÚAN Florenc.
Parking, taxis and toilets
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Getting to Praha, Na Knížecí from Prague city centre
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí bus station facilities and services
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility and WC.
Food and drink
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the entrance.
Parking, taxis and toilets
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Most popular bus connections from Rome
More options for your journey from Rome to Prague
Here are some other resources that might have the information you need


