The cheapest and fastest coaches from Madrid to Santander
- Cheapest price on 12 Nov
- $49
- Average ticket price on 12 Nov
- $52
- Fastest journey on 12 Nov
- 5 h 15 m
- Average journey duration on 12 Nov
- 5 h 21 m
- Buses on 12 Nov
- 13
- Distance
- 339 km
The best way to find a cheap coach ticket from Madrid to Santander is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Madrid to Santander will cost around $52 if you buy it on the day, but you can find cheap coach tickets today for only $49.
On Thu, 12 Nov, we found 13 buses from Madrid to Santander, including 12 direct services.
These direct buses cover the 339 km distance in an average of 5 h 21 m but if you time it right, some buses will get you there in just 5 h 15 m .
The slowest buses will take 5 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Normal1:00 PM 5h30 Madrid, Intercambiador de Avenida de América 6:30 PM Santander, Estación de Autobuses $49 1 One-way 0 changes
Normal6:45 PM 5h15 Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) 12:00 AM Santander, Estación de Autobuses $49 1 One-way 0 changes
Normal10:45 AM 5h30 Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) 4:15 PM Santander, Estación de Autobuses $49 1 One-way 0 changes
Normal4:30 PM 5h45 Madrid, Intercambiador de Avenida de América 10:15 PM Santander, Estación de Autobuses $49 1 One-way 0 changes
Normal4:45 PM 5h30 Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) 10:15 PM Santander, Estación de Autobuses $49 1 One-way 0 changes
Normal6:45 PM 5h15 Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) 12:00 AM Santander, Estación de Autobuses $49 1 One-way 0 changes
Supra Economy3:15 PM 5h15 Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) 8:30 PM Santander, Estación de Autobuses $57 1 One-way 0 changes
Normal1:15 PM 5h15 Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) 6:30 PM Santander, Estación de Autobuses $49 1 One-way 0 changes
Normal1:00 PM 5h30 Madrid, Intercambiador de Avenida de América 6:30 PM Santander, Estación de Autobuses $49 1 One-way 0 changes
Normal10:45 AM 5h30 Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) 4:15 PM Santander, Estación de Autobuses $49 1 One-way 0 changes
Journey information
Overview: Bus from Madrid to Santander
Buses from Madrid to Santander run on average 14 times per day, taking around 6h 31m. Cheap bus tickets for this journey start at $37 but you can travel from only $9 by train.
There are 13 coaches per day. The earliest coach runs at 00:30, the last at 23:35. The fastest coach covers the 339 km distance in 4h 25m.
Distance 339 km |
Average bus duration 6h 31m |
Cheapest ticket price $37 |
Buses per day 14 |
Direct buses 13 |
Fastest bus 4h 25m |
First bus 12:30 AM |
Last bus 11:35 PM |
Cheapest Month Jan |
Cheapest Day Sat |
High Season Jul - Sept |
Low Season Oct - Dec |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 91 days |
Frequently asked questions about your Madrid to Santander trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Madrid to Santander.
Live departures
Madrid to Santander bus times
The table below shows live departures for Madrid to Santander coaches for today, Wednesday, 11 November. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
Normal | 6:30 PM Madrid, Intercambiador de Avenida de América | 5h30 | 12:00 AM Santander, Estación de Autobuses | 0 changesdirect | |
Normal | 6:45 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 5h15 | 12:00 AM Santander, Estación de Autobuses | 0 changesdirect | |
| Thursday, 12 November | |||||
Supra Economy | 12:30 AM Madrid, Intercambiador de Avenida de América | 6h00 | 6:30 AM Santander, Estación de Autobuses | 0 changesdirect | |
Supra Economy | 12:45 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 5h45 | 6:30 AM Santander, Estación de Autobuses | 0 changesdirect | |
Normal | 10:30 AM Madrid, Intercambiador de Avenida de América | 5h45 | 4:15 PM Santander, Estación de Autobuses | 0 changesdirect | |
Normal | 10:45 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 5h30 | 4:15 PM Santander, Estación de Autobuses | 0 changesdirect | |
Normal | 1:00 PM Madrid, Intercambiador de Avenida de América | 5h30 | 6:30 PM Santander, Estación de Autobuses | 0 changesdirect | |
Normal | 1:15 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 5h15 | 6:30 PM Santander, Estación de Autobuses | 0 changesdirect | |
Supra Economy | 3:00 PM Madrid, Intercambiador de Avenida de América | 5h30 | 8:30 PM Santander, Estación de Autobuses | 0 changesdirect | |
Supra Economy | 3:15 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 5h15 | 8:30 PM Santander, Estación de Autobuses | 0 changesdirect | |
Normal | 4:30 PM Madrid, Intercambiador de Avenida de América | 5h45 | 10:15 PM Santander, Estación de Autobuses | 0 changesdirect | |
FlixBus · FlixBus | 4:40 PM Madrid, Estación Sur de Autobuses | 16h40 | 9:20 AM Santander, Estación de Autobuses | 1 change | |
Normal | 4:45 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 5h30 | 10:15 PM Santander, Estación de Autobuses | 0 changesdirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Madrid to Santander coaches with Omio?
Why book with Omio vs Alsa?
- Compare with other providers: On Omio, you can not only buy tickets for Alsa, but also compare tickets for the likes of Alsa Supra or FlixBus to find the best option for your trip from Madrid to Santander.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Alsa with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Madrid to Santander.
Why book with Omio over Checkmybus, Rome2rio or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Alsa Supra or FlixBus to find the best option for your trip from Madrid to Santander.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Madrid to Santander.
Bus providers: Alsa, FlixBus, Alsa Supra from Madrid to SantanderYou can travel by bus between Madrid to Santander with Alsa, FlixBus, Alsa Supra for as low as $9. When you search for schedules and tickets, Omio will show you the best journey
Alsa
FlixBus
Alsa Supra
Companies, tickets, and onboard amenities between Madrid and Santander
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
- Alsa
- Assistance
- Priority boarding
- Accessible seating.
- Alsa Supra
- Assistance
- Priority boarding
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Alsa
- You can cancel your ticket up to 48 hours before departure for a partial refund. Changes allowed for a fee.
- Alsa Supra
- You can cancel your ticket up to 48 hours before departure for a partial refund. Within 48 hours, a fee applies.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Alsa
- One carry-on bag up to 10kg and one checked bag up to 25kg.
- Alsa Supra
- One carry-on bag up to 10kg and one checked bag up to 25kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Alsa
- Additional luggage can be purchased for a fee.
- Alsa Supra
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Alsa
- Small pets allowed in carriers
- larger pets must travel in the hold.
- Alsa Supra
- Small pets allowed in carriers
- guide dogs travel for free.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
FAQs: Madrid to Santander coach
Find answers to the most common questions about traveling from Madrid to Santander by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Santander, this guide helps you travel smarter and with confidence.

popular bus stations
Important Stations and Airports in Madrid and Santander
Most Madrid to Santander buses use the Madrid, Avenida de América to Santander, Estación de Autobuses station pair. Use this guide to compare Madrid and Santander bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Madrid station do buses to Santander leave from?
Getting to Madrid, Avenida de América from Madrid city centre
Madrid, Avenida de América is 3 km from Madrid city centre. Public transport options include:
Madrid, Avenida de América bus station facilities and services
Madrid, Avenida de América has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food and drink
Food options include: Cafetería de la estación (in the station), Restaurante El Rincón (0.5 km), La Vaca Argentina (0.7 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and on the second floor.
Tickets and information
Ticket office support is available at Madrid, Avenida de América.
Parking, taxis and toilets
Available at Madrid, Avenida de América: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Madrid, Avenida de América: Elevators, ramps.
Getting to Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) from Madrid city centre
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) is 12 km from Madrid city centre. Public transport options include:
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) bus station facilities and services
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) has practical services for this route, including Dining, ATM, Accessibility, WC, Shower and Ticket Office.
Food and drink
Food options include: Rodilla, Mahoudrid
Wi-Fi and ATMs
ATMs are aTMs located throughout T4, major cards accepted .
Tickets and information
Ticket office support is available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid).
Parking, taxis and toilets
Available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): WC.
Accessibility
Accessibility facilities are available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): Step-free access, elevators, accessible toilets.
Getting to Madrid, Estación Sur de Autobuses from Madrid city centre
Madrid, Estación Sur de Autobuses is 3 km from Madrid city centre. Public transport options include:
Madrid, Estación Sur de Autobuses bus station facilities and services
Madrid, Estación Sur de Autobuses has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food and drink
Food options include: Cafetería de la estación (in the station), Restaurante El Brillante (0.5 km), La Taberna de Domínguez (0.7 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Tickets and information
Ticket office support is available at Madrid, Estación Sur de Autobuses.
Parking, taxis and toilets
Available at Madrid, Estación Sur de Autobuses: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Madrid, Estación Sur de Autobuses: Elevators, ramps.
Most popular bus connections from Madrid
More options for your journey from Madrid to Santander
Here are some other resources that might have the information you need

