The cheapest and fastest coaches from Lyon to Brussels
Cheapest price on 29 Sept
49S$
Average ticket price on 29 Sept
66S$
Fastest journey on 29 Sept
10 h 40 m
Average journey duration on 29 Sept
11 h 31 m
Buses on 29 Sept
7
Distance
569 km
The best way to find a cheap coach ticket from Lyon to Brussels is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Lyon to Brussels will cost around 66S$ if you buy it on the day, but you can find cheap coach tickets today for only 49S$.
On Tue, 29 Sept, we found 7 buses from Lyon to Brussels, including 1 direct services.
These direct buses cover the 569 km distance in an average of 11 h 31 m but if you time it right, some buses will get you there in just 10 h 40 m .
The slowest buses will take 12 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
5132 · 165711:55 PM12h05Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)12:00 PMBrussels, Brussels South (Gare du Midi)49 S$1One-way1 change
FlixBus · FlixBus3:15 PM11h50Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)3:05 AMBrussels, Brussels South (Gare du Midi)62 S$1One-way1 change
FlixBus · FlixBus12:10 AM12h10Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)12:20 PMBrussels, Brussels South (Gare du Midi)63 S$1One-way1 change
50618 · 16571:20 AM10h40Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)12:00 PMBrussels, Brussels South (Gare du Midi)63 S$1One-way1 change
FlixBus9:25 PM10h50Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)8:15 AMBrussels, Brussels South (Gare du Midi)66 S$1One-way0 changes
50618 · 16571:20 AM10h40Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)12:00 PMBrussels, Brussels South (Gare du Midi)63 S$1One-way1 change
FlixBus9:25 PM10h50Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)8:15 AMBrussels, Brussels South (Gare du Midi)66 S$1One-way0 changes
FlixBus · FlixBus3:15 PM11h50Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)3:05 AMBrussels, Brussels South (Gare du Midi)62 S$1One-way1 change
5132 · 165711:55 PM12h05Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)12:00 PMBrussels, Brussels South (Gare du Midi)49 S$1One-way1 change
FlixBus · FlixBus12:10 AM12h10Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)12:20 PMBrussels, Brussels South (Gare du Midi)63 S$1One-way1 change
Live departures
Lyon to Brussels bus times
The table below shows live departures for Lyon to Brussels coaches for today, Monday, 28 September. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FlixBus | 9:25 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 10h50 | 8:15 AM Brussels, Brussels South (Gare du Midi) | 0 changesdirect | |
5132 · 1657 | 11:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 12h05 | 12:00 PM Brussels, Brussels South (Gare du Midi) | 1 change | |
| Tuesday, 29 September | |||||
FlixBus · FlixBus | 12:10 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 12h10 | 12:20 PM Brussels, Brussels South (Gare du Midi) | 1 change | |
50618 · 1657 | 1:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 10h40 | 12:00 PM Brussels, Brussels South (Gare du Midi) | 1 change | |
FlixBus · FlixBus | 1:40 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 13h55 | 3:35 PM Brussels, Brussels South (Gare du Midi) | 1 change | |
FlixBus · FlixBus | 5:00 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 12h55 | 5:55 PM Brussels, Brussels South (Gare du Midi) | 1 change | |
FlixBus · FlixBus | 3:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 11h50 | 3:05 AM Brussels, Brussels South (Gare du Midi) | 1 change | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon to Brussels by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Lyon to Brussels coaches with Omio?
Why book with Omio vs BlaBlaCar Bus?
- Compare with other providers: On Omio, you can not only buy tickets for BlaBlaCar Bus, but also compare tickets for the likes of FlixBus to find the best option for your trip from Lyon to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare BlaBlaCar Bus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Lyon to Brussels.
Why book with Omio over Checkmybus, Wanderu or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Lyon to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Lyon to Brussels.
Journey information
Overview: Bus from Lyon to Brussels
Buses from Lyon to Brussels run on average 14 times per day, taking around 10h 7m. Cheap bus tickets for this journey start at 26S$ if you book in advance.
There are 2 coaches per day. The earliest coach runs at 00:10, the last at 23:55. The fastest coach covers the 569 km distance in 8h 25m.
Distance 569 km |
Average bus duration 10h 7m |
Cheapest ticket price 26S$ |
Buses per day 14 |
Direct buses 2 |
Fastest bus 8h 25m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Aug |
Cheapest Day Mon |
High Season Jul - Sept |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 84 days |
Bus providers: FlixBus, BlaBlaCar Bus from Lyon to BrusselsYou can travel by bus between Lyon to Brussels with FlixBus, BlaBlaCar Bus for as low as 26S$. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar Bus
FAQs: Lyon to Brussels coach
Find answers to the most common questions about traveling from Lyon to Brussels by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Important Stations and Airports in Lyon and Brussels
Most Lyon to Brussels buses use the Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) to Brussels, Brussels South (Gare du Midi) station pair, with some services arriving at Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord). Use this guide to compare Lyon and Brussels bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Lyon station do buses to Brussels leave from?
Getting to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) from Lyon city centre
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) bus station facilities and services
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Tickets and information
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Parking, taxis and toilets
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Getting to Lyon, Gare Routière de Perrache from Lyon city centre
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache bus station facilities and services
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food and drink
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance.
Tickets and information
Ticket office support is available at Lyon, Gare Routière de Perrache.
Parking, taxis and toilets
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Getting to Lyon, St Exupéry Aéroport from Lyon city centre
Lyon, St Exupéry Aéroport is 2 km from Lyon city centre. Public transport options include:
Lyon, St Exupéry Aéroport bus station facilities and services
Lyon, St Exupéry Aéroport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Lyon, St Exupéry Aéroport. ATMs are available at Lyon, St Exupéry Aéroport.
Tickets and information
Ticket office support is available at Lyon, St Exupéry Aéroport.
Parking, taxis and toilets
Available at Lyon, St Exupéry Aéroport: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, St Exupéry Aéroport: Access ramps and services available.
Which Brussels station do buses from Lyon arrive at?
Getting to Brussels, Brussels South (Gare du Midi) from Brussels city centre
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) bus station facilities and services
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food and drink
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Tickets and information
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Parking, taxis and toilets
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Getting to Brussels, Gare Du Midi from Brussels city centre
Brussels, Gare Du Midi is 1 km from Brussels city centre. Public transport options include:
Brussels, Gare Du Midi bus station facilities and services
Brussels, Gare Du Midi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Food and drink
Food options include: Various dining options are nearby.
Wi-Fi and ATMs
Wi-Fi is available at Brussels, Gare Du Midi. ATMs are available at Brussels, Gare Du Midi.
Tickets and information
Ticket office support is available at Brussels, Gare Du Midi.
Parking, taxis and toilets
Available at Brussels, Gare Du Midi: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussels, Gare Du Midi: Station is accessible for individuals with disabilities.
Getting to Brussel, Avenue des Magnolias (Koning Boudewijn) from Brussels city centre
Brussel, Avenue des Magnolias (Koning Boudewijn) is 5 km from Brussels city centre. Public transport options include:
Brussel, Avenue des Magnolias (Koning Boudewijn) bus station facilities and services
Brussel, Avenue des Magnolias (Koning Boudewijn) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Brussel, Avenue des Magnolias (Koning Boudewijn). ATMs are available at Brussel, Avenue des Magnolias (Koning Boudewijn).
Tickets and information
Ticket office support is available at Brussel, Avenue des Magnolias (Koning Boudewijn).
Parking, taxis and toilets
Available at Brussel, Avenue des Magnolias (Koning Boudewijn): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussel, Avenue des Magnolias (Koning Boudewijn): Accessible for people with reduced mobility.
More options for your journey from Lyon to Brussels
Here are some other resources that might have the information you need
