The cheapest and fastest coaches from Isernia to Rome
Cheapest price
22S$
Average price
23S$
Fastest journey
2 h 25 m
Average duration
2 h 28 m
Buses per day
8
Distance
149 km
The best way to find a cheap coach ticket from Isernia to Rome is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Isernia to Rome will cost around 23S$ if you buy it on the day, but you can find cheap coach tickets today for only 22S$.
Of the 8 buses that leave Isernia for Rome every day 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct buses cover the 149 km distance in an average of 2 h 28 m but if you time it right, some buses will get you there in just 2 h 25 m .
The slowest buses will take 2 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus11:35 AM2h25Isernia, Piazza della Repubblica (F. Martino bus station)2:00 PMRoma, Autostazione Tiburtina22 S$1One-way0 changes
treno 23361 effettuato con bus CB7158:40 PM2h30Isernia station11:10 PMRome Termini22 S$1One-way0 changes
treno 23359 effettuato con bus CB7136:10 PM2h30Isernia station8:40 PMRome Termini22 S$1One-way0 changes
treno 23351 effettuato con bus CB7073:15 PM2h30Isernia station5:45 PMRome Termini22 S$1One-way0 changes
treno 23347 effettuato con bus CB7038:50 AM2h30Isernia station11:20 AMRome Termini22 S$1One-way0 changes
0598:25 AM2h25Isernia, Piazza della Repubblica (F. Martino bus station)10:50 AMRoma, Autostazione Tiburtina28 S$1One-way0 changes
FlixBus11:35 AM2h25Isernia, Piazza della Repubblica (F. Martino bus station)2:00 PMRoma, Autostazione Tiburtina22 S$1One-way0 changes
treno 23361 effettuato con bus CB7158:40 PM2h30Isernia station11:10 PMRome Termini22 S$1One-way0 changes
treno 23359 effettuato con bus CB7136:10 PM2h30Isernia station8:40 PMRome Termini22 S$1One-way0 changes
treno 23351 effettuato con bus CB7073:15 PM2h30Isernia station5:45 PMRome Termini22 S$1One-way0 changes
Travel Information
Compare train and coach for Isernia to Rome
Omio recommends booking the train as it is the most popular option from Isernia to Rome among Omio's users. If you are prioritising price take the train with prices starting from 21S$. For those with little time consider booking a coach which can get you there in 2h 22m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.0 - 0.1kg. The ticket price range depends on the travel mode: a train costs an average of 21S$, and a coach costs an average of 13S$.
Distance: 149 km
Compare bus with
| Coach | Most popular Train |
|---|---|
24S$ Average Price | 22S$ Average Price Cheapest |
2h 52m Average total duration Fastest 2h 22m Onboard + 30m Additional time* | 3h 28m Average total duration 2h 58m Onboard + 30m Additional time* |
0.1 - 0.4kg CO2 emissions | 0.0 - 0.1kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Isernia to Rome bus times
The table below shows live departures for Isernia to Rome coaches for today, Wednesday, 19 August. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
treno 23359 effettuato con bus CB713 | 6:10 PM Isernia station | 2h30 | 8:40 PM Rome Termini | 0 changesdirect | |
FlixBus · FlixBus | 6:15 PM Isernia, Piazza della Repubblica (F. Martino bus station) | 5h50 | 12:05 AM Roma, Autostazione Tiburtina | 1 change | |
treno 23361 effettuato con bus CB715 | 8:40 PM Isernia station | 2h30 | 11:10 PM Rome Termini | 0 changesdirect | |
| Thursday, 20 August | |||||
treno 23341 effettuato con bus CB701 | 6:50 AM Isernia station | 2h30 | 9:20 AM Rome Termini | 0 changesdirect | |
059 | 8:25 AM Isernia, Piazza della Repubblica (F. Martino bus station) | 2h25 | 10:50 AM Roma, Autostazione Tiburtina | 0 changesdirect | |
treno 23347 effettuato con bus CB703 | 8:50 AM Isernia station | 2h30 | 11:20 AM Rome Termini | 0 changesdirect | |
FlixBus | 11:35 AM Isernia, Piazza della Repubblica (F. Martino bus station) | 2h25 | 2:00 PM Roma, Autostazione Tiburtina | 0 changesdirect | |
treno 23349 effettuato con bus CB705 | 1:40 PM Isernia station | 2h30 | 4:10 PM Rome Tiburtina | 0 changesdirect | |
treno 23351 effettuato con bus CB707 | 3:15 PM Isernia station | 2h30 | 5:45 PM Rome Termini | 0 changesdirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Isernia to Rome by train or coach
Compare train and coach prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
20 Aug
21 Aug
22 Aug
23 Aug
24 Aug
25 Aug
26 Aug
Why should you book Isernia to Rome coaches with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of ATM Azienda di Trasporti Molisana S.p.A. to find the best option for your trip from Isernia to Rome.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Isernia to Rome.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Isernia to Rome.
Journey information
Overview: Bus from Isernia to Rome
Buses from Isernia to Rome run on average 10 times per day, taking around 2h 22m. Cheap bus tickets for this journey start at 13S$ if you book in advance.
There are 6 coaches per day. The earliest coach runs at 00:15, the last at 23:56. The fastest coach covers the 149 km distance in 2h 10m.
Distance 149 km |
Average bus duration 2h 22m |
Cheapest ticket price 13S$ |
Buses per day 10 |
Direct buses 6 |
Fastest bus 2h 10m |
First bus 12:15 AM |
Last bus 11:56 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Jul - Sept |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Mon |
Best time to book 35 days |
Bus providers: FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A. from Isernia to RomeYou can travel by bus between Isernia to Rome with FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A. for as low as 13S$. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
ATM Azienda di Trasporti Molisana S.p.A.
FAQs: Isernia to Rome coach
Find answers to the most common questions about traveling from Isernia to Rome by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Important Stations and Airports in Isernia and Rome
Most Isernia to Rome buses use the Isernia, Piazza della Repubblica (Autostazione F. Martino) to Roma, Autostazione Tiburtina station pair. Use this guide to compare Isernia and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Isernia station do buses to Rome leave from?
Getting to Isernia, Piazza della Repubblica (Autostazione F. Martino) from Isernia city centre
Isernia, Piazza della Repubblica (Autostazione F. Martino) bus station facilities and services
Isernia, Piazza della Repubblica (Autostazione F. Martino) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Food and drink
Food options include: Nearby cafés and fast food outlets.
Wi-Fi and ATMs
Wi-Fi is available at Isernia, Piazza della Repubblica (Autostazione F. Martino). ATMs are aTM located near the entrance.
Tickets and information
Ticket office support is available at Isernia, Piazza della Repubblica (Autostazione F. Martino).
Parking, taxis and toilets
Available at Isernia, Piazza della Repubblica (Autostazione F. Martino): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Isernia, Piazza della Repubblica (Autostazione F. Martino): Wheelchair accessible facility.
Which Rome station do buses from Isernia arrive at?
Getting to Roma, Autostazione Tiburtina from Rome city centre
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina bus station facilities and services
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Food and drink
Food options include: Cafes and vending machines available.
Wi-Fi and ATMs
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Tickets and information
Ticket office support is available at Roma, Autostazione Tiburtina.
Parking, taxis and toilets
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
More options for your journey from Isernia to Rome
Here are some other resources that might have the information you need
